UBA3

Gene Symbol UBA3
Entrez Gene 9039
Alt Symbol NAE2, UBE1C, hUBA3
Species Human
Gene Type protein-coding
Description ubiquitin-like modifier activating enzyme 3
Other Description NEDD8-activating enzyme E1 catalytic subunit|NEDD8-activating enzyme E1 subunit 2|NEDD8-activating enzyme E1C|Nedd8-activating enzyme hUba3|UBA3, ubiquitin-activating enzyme E1 homolog|ubiquitin-activating enzyme 3|ubiquitin-activating enzyme E1C (UBA3 homolog, yeast)|ubiquitin-activating enzyme E1C (homologous to yeast UBA3)|ubiquitin-like modifier-activating enzyme 3
Swissprots Q9NTU3 O76088 A8K027 Q8TBC4 A6NLB5
Accessions CDM22118 EAW65470 Q8TBC4 AB012190 BAA33144 AF046024 AAC27648 AK002159 BAG51021 AK289392 BAF82081 AK298878 BAH12892 AK314751 BAG37290 AK316540 BAH14911 AL117566 CAB55996 AM392893 CAL37771 AM393088 CAL37966 BC022853 AAH22853 BG940987 CD700642 CR533537 CAG38568 DQ893167 ABM84093 DQ896465 ABM87464 XM_011534210 XP_011532512 XM_011534211 XP_011532513 NM_003968 NP_003959 NM_198195 NP_937838 NM_198197
Function Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression. {ECO:0000269|PubMed:10207026, ECO:0000269|PubMed:12740388, ECO:0000269|PubMed:9694792}.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:10207026}.
Top Pathways Ubiquitin mediated proteolysis

Human-UBA3-cDNA-Clone - DC05326 from Abgent, a WuXi AppTec company

Prices $625.05
Sizes 10 µg
Species Human
Accession BC022853

UBA3 - MBS1271741 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC022853

Human UBA3 cDNA clone(NM_198195.1) - CDFG012645 from Creative Biomart

Species Human
Accession NM_198195.1

Human UBA3 cDNA clone(NM_003968.3) - CDFH020709 from Creative Biomart

Species Human
Accession NM_003968.3

Human UBA3 ORF Clone(NM_003968.3) - CDCR286876 from Creative Biomart

Species Human
Accession NM_003968.3

Human UBA3 ORF Clone(NM_003968.3) - CDCR286877 from Creative Biomart

Species Human
Accession NM_003968.3

Human UBA3 ORF Clone(NM_198195.1) - CDCR325580 from Creative Biomart

Species Human
Accession NM_198195.1

Human UBA3 ORF Clone(NM_198195.1) - CDCR325581 from Creative Biomart

Species Human
Accession NM_198195.1

Human UBA3 ORF Clone(NM_198195.1) - CDCR325582 from Creative Biomart

Species Human
Accession NM_198195.1

human UBA3 ORF clone - CDCH097192 from Creative Biomart

Species Human
Accession NM_003968

human UBA3 ORF clone - CDCH097193 from Creative Biomart

Species Human
Accession NM_003968

human UBA3 ORF clone - CDCH097194 from Creative Biomart

Species Human
Accession NM_003968

human UBA3 ORF clone - CDCH097195 from Creative Biomart

Species Human
Accession NM_003968

human UBA3 ORF clone - CDCH097196 from Creative Biomart

Species Human
Accession NM_003968

human UBA3 ORF clone - CDCH097197 from Creative Biomart

Species Human
Accession NM_003968

Human UBA3 Gene cDNA Clone (full-length ORF Clone) - HG16320-G from Sino Biological

Species Human
Accession NM_003968.3

Human UBA3 natural ORF mammalian expression plasmid, N-His tag - HG16320-NH from Sino Biological

Species Human
Accession NM_003968.3

Human UBA3 natural ORF mammalian expression plasmid, C-GFPSpark tag - HG16320-ACG from Sino Biological

Species Human
Accession NM_003968.3

Human UBA3 natural ORF mammalian expression plasmid, N-GFPSpark tag - HG16320-ANG from Sino Biological

Species Human
Accession NM_003968.3

Human UBA3 natural ORF mammalian expression plasmid, N-HA tag - HG16320-NY from Sino Biological

Species Human
Accession NM_003968.3
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