NDP

Gene Symbol	NDP
Entrez Gene	4693
Alt Symbol	EVR2, FEVR, ND
Species	Human
Gene Type	protein-coding
Description	Norrie disease (pseudoglioma)
Other Description	X-linked exudative vitreoretinopathy 2 protein|norrie disease protein|norrin
Swissprots	B2R8K6 Q00604 Q5JYH5
Accessions	EAW59376 Q00604 AK313409 BAG36203 AM392592 CAL37470 BC029901 AAH29901 BE139596 DA714180 X65724 CAA46639 X65882 CAA46713 NM_000266 NP_000257
Function	Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction.
Subcellular Location	Secreted {ECO:0000269|PubMed:9407136}.
Tissue Specificity	Expressed in the outer nuclear, inner nuclear and ganglion cell layers of the retina, and in fetal and adult brain. {ECO:0000269|PubMed:10452356}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NDP ELISA Kit (Sandwich ELISA) - LS-F12129 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.312-20 ng/ml

Norrin (NDP), Human, ELISA Kit - CSB-EL015609HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Norrin, NDP, Human, ELISA Kit - E14889h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 0.312-20 ng/mL

Norrie disease (pseudoglioma) , ELISA Kit - MBS901439 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Human Norrin(NDP) ELISA kit - CSB-EL015609HU from Cusabio Category ELISA Kit Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Mouse NDP ELISA Kit (Sandwich ELISA) - LS-F17469 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 ng/ml Range 0.312-20 ng/ml

Bovine NDP ELISA Kit (Custom ELISA) - LS-F17470 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.312-20 ng/ml

Custom Human Norrin ELISA - ELH-NORN from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human Norrin ELISA Kit - abx250960 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Custom Human Norrin Elisa kit - orb305352 from Biorbyt Category ELISA Kit Prices $1,148.00, $1,981.00, $4,284.00 Sizes 96 assays, 192 assays, 480 assays

Human Norrin ELISA - RAB1602 from Sigma-Aldrich Prices $615.00 Sizes 1 kt

Human Norrin (NDP) ELISA Kit - EKC34842 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

Human Norrin ELISA Kit - EKE55123 from Biomatik Category ELISA Kit Prices $809.60, $3,440.80, $6,476.80 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.23 ng/ml Range 0.312-20 ng/mL

NDP - EKH3328 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

NDP ELISA Kit (Human) : 96 Wells (OKEH02379) - OKEH02379 from Aviva Systems Biology Category ELISA Kit Prices $480.00 Sizes 96 wells Sensitivity < 0.23 ng/mL Range 0.312 - 20 ng/mL

Human Norrin ELISA - ELH-NORN-1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human EVR2 ELISA Kit - E013920 from Biobool Category ELISA Kit

Human NDP ELISA Kit - E026781 from Biobool Category ELISA Kit Sensitivity Typically less than 0.078 ng/ml.

Human Norrin ELISA Kit - EK3485 from Signalway Antibody Category ELISA Kit Prices $739.00 Sizes 1x96t Sensitivity less than 0.23ng/ml Range 0.312-20 ng/mL

Norrin, ELISA Kit - MBS9427319 from MyBioSource Category ELISA Kit Prices $670.00 Sizes 96 tests Sensitivity Less than 0.23ng/mL Range 0.312-20 ng/mL

Norrin, ELISA Kit - MBS2882998 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.312-20 ng/mL

Norrin, ELISA Kit - MBS762296 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/ml Range 0.312-20ng/ml

Human NDP ELISA Kit (Sandwich ELISA) - LS-F33241 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.188 Range 0.312-20 ng/ml

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