NDP

Gene Symbol NDP
Entrez Gene 4693
Alt Symbol EVR2, FEVR, ND
Species Human
Gene Type protein-coding
Description Norrie disease (pseudoglioma)
Other Description X-linked exudative vitreoretinopathy 2 protein|norrie disease protein|norrin
Swissprots B2R8K6 Q00604 Q5JYH5
Accessions EAW59376 Q00604 AK313409 BAG36203 AM392592 CAL37470 BC029901 AAH29901 BE139596 DA714180 X65724 CAA46639 X65882 CAA46713 NM_000266 NP_000257
Function Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction.
Subcellular Location Secreted {ECO:0000269|PubMed:9407136}.
Tissue Specificity Expressed in the outer nuclear, inner nuclear and ganglion cell layers of the retina, and in fetal and adult brain. {ECO:0000269|PubMed:10452356}.

NORRIN (FL-133) - sc-134736 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NORRIN (FL-133): sc-134736. Western blot analysis of NORRIN expression in mouse eye (A) and rat eye (B) tissue extracts.

NORRIN (S-20) - sc-49311 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NORRIN (B-8) - sc-377276 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NORRIN (B-8): sc-377276. Western blot analysis of NORRIN expression in mouse eye (A) and rat eye (B) tissue extracts.

Anti-NDP antibody - ab185715 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NDP antibody (ab185715) at 1/500 dilutionLane 1 : Mouse liver cell line extractLane 2 : Mouse heart cell line extractLane 3 : Mouse eye cell line extract

Anti-NDP antibody - ab106381 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-NDP antibody (ab106381) at 1 µg/mlLane 2 : Anti-NDP antibody (ab106381) at 2 µg/mlLane 1 : Jurkat cell lysate Lane 2 : Jurkat cell lysate Lysates/proteins at 15 µg per lane.

Anti-NDP Antibody (aa25-133) - LS-C37741 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-NDP Antibody - LS-C341392 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NDP Antibody - LS-C331790 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using NDP antibody.

Anti-NDP Antibody (N-Terminus) - LS-C108494 from LifeSpan Bioscience

Prices $345.00, $1,035.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry of Norrin in Jurkat cells with Norrin antibody at 5 ug/ml.

Norrin/NDP Antibody - AF3014 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

Norrin/NDP Antibody - NBP1-59305 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NDP/Norrin Antibody [NBP1-59305] - Fetal Liver tissue lysate at a concentration of 1ug/ml.

Norrin/NDP Antibody (343711) - MAB3014 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 343711

Norrin/NDP Antibody - NBP1-84769 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Norrin/NDP Antibody - NBP1-77014 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Norrin/NDP Antibody [NBP1-77014] - Jurkat cell lysate with Norrin antibody at (A) 1 and (B) 2 ug/mL.

Norrin/NDP Antibody - H00004693-B02P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Norrin/NDP Antibody [H00004693-B02P] - Analysis of NDP expression in transfected 293T cell line by NDP polyclonal antibody. Lane 1: NDP transfected lysate(14.63 KDa). Lane 2: Non-transfected lysate.

Norrin/NDP Antibody [Biotin] - BAF3014 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-NORRIN antibody produced in chicken - SAB3500031 from Sigma-Aldrich

Prices $316.00
Sizes 100 µg
Host Chicken
Clonality Polyclonal
<B>Immunocytochemistry</B><BR/>Anti-Norrin: <B>Cat. No. SAB3500031</B>: Norrin in Jurkat cells with Norrin antibody at 5 μg/mL.

Anti-NDP antibody produced in mouse - SAB1406165 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-NDP: <B>Cat. No. SAB1406165</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~14.6 kDa using NDP transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-NDP antibody produced in rabbit - HPA003095 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NDP: <B>Cat. No. HPA003095</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing strong cytoplasmic staining of cells in distal tubuli and nuclear staining of cells in glomeruli.

Anti-NDP antibody produced in rabbit - SAB2104054 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NDP: <B>Cat. No. SAB2104054</B>: Immunohistochemistry of NDP in Brain, cortex tissue with NDP antibody at 4-8 μg/mL.

NDP antibody - middle region (ARP56082_P050) - ARP56082_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Norrin antibody - GTX85292 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-Norrin antibody used in Western blot. GTX85292

Human/Mouse Norrin Antibody - MAB3014 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 343711

Human/Mouse Norrin MAb (Clone 343711), Mouse IgG1 - MAB3014-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 343711

Human Norrin Antibody - AF3014 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
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