HSH2D

Gene Symbol HSH2D
Entrez Gene 84941
Alt Symbol ALX, HSH2
Species Human
Gene Type protein-coding
Description hematopoietic SH2 domain containing
Other Description adaptor in lymphocytes of unknown function X|hematopoietic SH2 domain-containing protein
Swissprots Q6ZNG7 B5ME72 Q96JZ2
Accessions EAW84528 EAW84529 EAW84530 EAW84531 EAW84532 Q96JZ2 AK027792 BAB55372 AK131222 BAD18408 AK298682 BAG60845 AK300027 BAG61838 AK307563 AY319652 AAQ81285 BC016826 AAH16826 BC025237 AAH25237 BF511682 DQ892165 ABM83091 DQ895359 ABM86285 XM_011528386 XP_011526688 XM_011528387 XP_011526689 XM_011528388 XP_011526690 XM_011528389 XP_011526691 XM_011528390 XP_011526692 NM_001291274 NP_001278203 NM_032855 NP_116244 NR_111903 NR_111904
Function May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter. {ECO:0000250, ECO:0000269|PubMed:11700021, ECO:0000269|PubMed:12960172, ECO:0000269|PubMed:15284240}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Predominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and weakly expressed in prostate, thymus, heart, small intestine and placenta. {ECO:0000269|PubMed:11700021, ECO:0000269|PubMed:12960172}.

HSH2 (C-14) - sc-240561 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

HSH2 (K-15) - sc-240559 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-HSH2D antibody - ab169172 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-HSH2D antibody (ab169172) at 1 µg/mlLane 1 : HSH2D transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat anti-mouse HRP at 1/2500 dilution

Anti-HSH2D antibody - ab67413 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-HSH2D antibody (ab67413) at 1/500 dilutionLane 1 : Transfected 293T cell line Lane 2 : Non transfected 293T cell line Lysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-HSH2D antibody - ab101039 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-HSH2D antibody (ab101039) at 0.3 µg/ml + K-562 Cell Lysate (in RIPA buffer) at 35 µg

Anti-HSH2D antibody - ab128326 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HSH2D antibody (ab128326) at 1 µg/ml + COLO205 cell lysate at 10 µg

Anti-ALX / HSH2D Antibody (aa325-339) - LS-C112948 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ALX / HSH2D Antibody - LS-C308333 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ALX / HSH2D Antibody (C-Terminus) - LS-C151400 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ALX / HSH2D antibody Western Blot of COLO205.

Anti-ALX / HSH2D Antibody (aa267-316) - LS-C135857 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HSH2D antibody LS-C135857 Western blot of Fetal Kidney lysate.

Anti-ALX / HSH2D Antibody (clone 1D6) - LS-C134113 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D6
Immunoperoxidase of monoclonal antibody to HSH2D on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]

Anti-ALX / HSH2D Antibody (aa62-74) - LS-C112947 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
HSH2D antibody (0.3 ug/ml) staining of K562 lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

HSH2D Antibody - H00084941-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: HSH2D Antibody [H00084941-B01P] - Analysis of HSH2D expression in transfected 293T cell line by HSH2D polyclonal antibody. Lane 1: HSH2D transfected lysate(38.83 KDa). Lane 2: Non-transfected lysate.

HSH2D Antibody - H00084941-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: HSH2D Antibody [H00084941-B01] - analysis of HSH2D expression in transfected 293T cell line by HSH2D MaxPab polyclonal antibody (B01). Lane 1: HSH2D transfected lysate (38.83 KDa). Lane 2: Non-transfected lysate.

HSH2D Antibody (1D6) - H00084941-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D6
Immunohistochemistry-Paraffin: HSH2D Antibody (1D6) [H00084941-M01] - Analysis of monoclonal antibody to HSH2D on formalin-fixed paraffin-embedded human placenta. Antibody concentration 3 ug/ml.

HSH2D Antibody - NBP1-89109 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: HSH2D Antibody [NBP1-89109] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

HSH2D Antibody - NBP1-52023 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: HSH2D Antibody [NBP1-52023] - (0.3ug/ml) staining of K562 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

HSH2D Antibody - NBP1-79862 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

HSH2D Antibody - H00084941-B02P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: HSH2D Antibody [H00084941-B02P] - Analysis of HSH2D expression in transfected 293T cell line by HSH2D polyclonal antibody. Lane 1: HSH2D transfected lysate(38.72 KDa). Lane 2: Non-transfected lysate.

HSH2D Antibody - H00084941-B02 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: HSH2D Antibody [H00084941-B02] - analysis of HSH2D expression in transfected 293T cell line by HSH2D MaxPab polyclonal antibody (B02). Lane 1: HSH2D transfected lysate (39.00 KDa). Lane 2: Non-transfected lysate.

HSH2D Antibody - NBP1-52156 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Rabbit Anti-HSH2D Polyclonal Antibody - bs-13643R from Bioss

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-HSH2D Polyclonal Antibody, Unconjugated (bs-13643R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

Rabbit Anti-HSH2D Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13643R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HSH2D Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13643R-A488 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HSH2D Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13643R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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