HSH2D

Gene Symbol HSH2D
Entrez Gene 84941
Alt Symbol ALX, HSH2
Species Human
Gene Type protein-coding
Description hematopoietic SH2 domain containing
Other Description adaptor in lymphocytes of unknown function X|hematopoietic SH2 domain-containing protein
Swissprots Q6ZNG7 B5ME72 Q96JZ2
Accessions EAW84528 EAW84529 EAW84530 EAW84531 EAW84532 Q96JZ2 AK027792 BAB55372 AK131222 BAD18408 AK298682 BAG60845 AK300027 BAG61838 AK307563 AY319652 AAQ81285 BC016826 AAH16826 BC025237 AAH25237 BF511682 DQ892165 ABM83091 DQ895359 ABM86285 XM_011528386 XP_011526688 XM_011528387 XP_011526689 XM_011528388 XP_011526690 XM_011528389 XP_011526691 XM_011528390 XP_011526692 NM_001291274 NP_001278203 NM_032855 NP_116244 NR_111903 NR_111904
Function May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter. {ECO:0000250, ECO:0000269|PubMed:11700021, ECO:0000269|PubMed:12960172, ECO:0000269|PubMed:15284240}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Predominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and weakly expressed in prostate, thymus, heart, small intestine and placenta. {ECO:0000269|PubMed:11700021, ECO:0000269|PubMed:12960172}.

Human HSH2D full length protein - ab164703 from Abcam

Category Protein
Source Wheat germ
Species Human
ab164703 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human HSH2D protein fragment - ab164704 from Abcam

Category Protein
Source Wheat germ
Species Human
ab164704 on a 12.5% SDS-PAGE stained with Coomassie Blue.

ALX / HSH2D Antibody Blocking Peptide - LS-E22208 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALX / HSH2D Antibody Blocking Peptide - LS-E22209 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALX / HSH2D Antibody Blocking Peptide - LS-E27312 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ALX / HSH2D Antibody Blocking Peptide - LS-E27311 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human HSH2D Protein - H00084941-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human HSH2D Protein - H00084941-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

HSH2D (aa325-339) blocking peptide - GTX88193-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human

HSH2D blocking peptide - GTX88192-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse

HSH2D Blocking Peptide - 33R-2096 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

HSH2D Peptide - AC21-2134-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

HSH2D Peptide - AC21-2135-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

HSH2D / ALX - H00084941-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

HSH2D / ALX - H00084941-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

HSH2D / ALX - H00084941-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

HSH2D / ALX - H00084941-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

HSH2D Peptide - 42-539P from ProSci

Category Peptide

HSH2D Peptide - 42-538P from ProSci

Category Peptide
Species Human

HSH2D fusion protein - ag2363 from Proteintech Group

Category Protein
Source E. coli-derived, T-HIS
Species Human

Recombinant Human Hematopoietic SH2 domain-containing protein(HSH2D) - CSB-YP850321HU CSB-EP850321HU CSB-BP850321HU CSB-MP850321HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

HSH2D / ALX - TP306816 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
HSH2D / ALX

HSH2D, Peptide - MBS428433 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse

HSH2D, Peptide - MBS427229 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human

HSH2D Protein - NBP1-89109PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human
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