HSH2D

Gene Symbol	HSH2D
Entrez Gene	84941
Alt Symbol	ALX, HSH2
Species	Human
Gene Type	protein-coding
Description	hematopoietic SH2 domain containing
Other Description	adaptor in lymphocytes of unknown function X|hematopoietic SH2 domain-containing protein
Swissprots	Q6ZNG7 B5ME72 Q96JZ2
Accessions	EAW84528 EAW84529 EAW84530 EAW84531 EAW84532 Q96JZ2 AK027792 BAB55372 AK131222 BAD18408 AK298682 BAG60845 AK300027 BAG61838 AK307563 AY319652 AAQ81285 BC016826 AAH16826 BC025237 AAH25237 BF511682 DQ892165 ABM83091 DQ895359 ABM86285 XM_011528386 XP_011526688 XM_011528387 XP_011526689 XM_011528388 XP_011526690 XM_011528389 XP_011526691 XM_011528390 XP_011526692 NM_001291274 NP_001278203 NM_032855 NP_116244 NR_111903 NR_111904
Function	May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter. {ECO:0000250, ECO:0000269|PubMed:11700021, ECO:0000269|PubMed:12960172, ECO:0000269|PubMed:15284240}.
Subcellular Location	Cytoplasm. Nucleus.
Tissue Specificity	Predominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and weakly expressed in prostate, thymus, heart, small intestine and placenta. {ECO:0000269|PubMed:11700021, ECO:0000269|PubMed:12960172}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HSH2 293T Cell Transient Overexpression Lysate(Denatured) - H00084941-T02 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

HSH2D 293T Cell Transient Overexpression Lysate(Denatured) - H00084941-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

HSH2D overexpression lysate - LY409889 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

HSH2D Overexpression Lysate (Denatured) - H00084941-T01 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

HSH2D Overexpression Lysate (Denatured) - H00084941-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl Species Human

HSH2D Overexpression Lysate (Native) - NBP2-05959 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human HSH2D Knockdown Stable Cell Line - CSC-DC007300 from Creative biogene Category Cell Line Species Human

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