HSH2D

Gene Symbol HSH2D
Entrez Gene 84941
Alt Symbol ALX, HSH2
Species Human
Gene Type protein-coding
Description hematopoietic SH2 domain containing
Other Description adaptor in lymphocytes of unknown function X|hematopoietic SH2 domain-containing protein
Swissprots Q6ZNG7 B5ME72 Q96JZ2
Accessions EAW84528 EAW84529 EAW84530 EAW84531 EAW84532 Q96JZ2 AK027792 BAB55372 AK131222 BAD18408 AK298682 BAG60845 AK300027 BAG61838 AK307563 AY319652 AAQ81285 BC016826 AAH16826 BC025237 AAH25237 BF511682 DQ892165 ABM83091 DQ895359 ABM86285 XM_011528386 XP_011526688 XM_011528387 XP_011526689 XM_011528388 XP_011526690 XM_011528389 XP_011526691 XM_011528390 XP_011526692 NM_001291274 NP_001278203 NM_032855 NP_116244 NR_111903 NR_111904
Function May be a modulator of the apoptotic response through its ability to affect mitochondrial stability (By similarity). Adapter protein involved in tyrosine kinase and CD28 signaling. Seems to affect CD28-mediated activation of the RE/AP element of the interleukin-2 promoter. {ECO:0000250, ECO:0000269|PubMed:11700021, ECO:0000269|PubMed:12960172, ECO:0000269|PubMed:15284240}.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Predominantly expressed in spleen and hematopoietic cells such as peripheral blood leukocytes and weakly expressed in prostate, thymus, heart, small intestine and placenta. {ECO:0000269|PubMed:11700021, ECO:0000269|PubMed:12960172}.

HSH2 CRISPR/Cas9 KO Plasmid (h) - sc-413743 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSH2 HDR Plasmid (h) - sc-413743-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSH2 Double Nickase Plasmid (h) - sc-413743-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSH2 Double Nickase Plasmid (h2) - sc-413743-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSH2 CRISPR Activation Plasmid (h) - sc-413743-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSH2 CRISPR Activation Plasmid (h2) - sc-413743-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSH2 Lentiviral Activation Particles (h) - sc-413743-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSH2 Lentiviral Activation Particles (h2) - sc-413743-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HSH2 siRNA (h) - sc-97691 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HSH2 shRNA Plasmid (h) - sc-97691-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HSH2 shRNA (h) Lentiviral Particles - sc-97691-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU073711 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10346 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10346 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06437 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06437

HSH2D siRNA (Human) - CRJ3712 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HSH2D - MBS8229005 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HSH2D (NM_032855.2) - SHH315453 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human HSH2D(NM_032855.2) - SHH133571 from Creative biogene

Category siRNA
Species Reactivities Human

Human HSH2D siRNA - orb274213 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HSH2D shRNA Plasmid (Human) - CHJ3712 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HSH2D miRNA 3'UTR clone - MiUTR1H-04726 from Creative biogene

Species Reactivities Human
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