NANOS3

Gene Symbol	NANOS3
Entrez Gene	342977
Alt Symbol	NANOS1L, NOS3
Species	Human
Gene Type	protein-coding
Description	nanos homolog 3 (Drosophila)
Other Description	nanos homolog 3
Swissprots	Q495E5 P60323
Accessions	P60323 BC101209 AAI01210 BC101210 AAI01211 BI793167 CK821051 CK821052 DN993610 XM_011527964 XP_011526266 NM_001098622 NP_001092092
Function	Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax- dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis. {ECO:0000269|PubMed:21421998}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:21421998}. Cytoplasm {ECO:0000269|PubMed:21421998}. Cytoplasmic granule {ECO:0000250}. Cytoplasm, P-body {ECO:0000250}. Note=The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with PUM2, EIF2S1 and TIAL1 in the stress granules. Colocalizes with DCP1A in the P-body (By similarity). {ECO:0000250}.
Tissue Specificity	Ovary, testis and brain (at protein level). In the ovaries, expressed during multiple stages of oogenesis, including primordial, primary, secondary and antral follicles with the highest expression in the oocytes. In the testis, expressed in germ cells, type A spermatogonia (SA), primary spermatocytes (S1), round spermatids (S3) and elongated spermatids. {ECO:0000269|PubMed:21421998}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Nanos3 protein fragment - ab153643 from Abcam Category Protein Source Wheat germ Species Human

Nanos3 peptide - ab176129 from Abcam Category Peptide

NANOS3 / NOS-3 Antibody Blocking Peptide - LS-E30520 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NANOS3 / NOS-3 Antibody Blocking Peptide - LS-E30524 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NOS3 / eNOS Antibody Blocking Peptide - LS-E1248 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NOS3 / eNOS Antibody Blocking Peptide - LS-E7451 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NOS3 / eNOS Antibody Blocking Peptide - LS-E8574 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

eNOS Partial Recombinant Protein - H00004846-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Nanos3 Protein - H00342977-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Nanos3 Blocking Peptide - NBP1-76919PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Nanos3 Peptide - GTX85389-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Recombinant rat Nanos homolog 3 protein (OPCA01106) - OPCA01106 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Rat

NANOS3 - H00342977-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NANOS3 - H00342977-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NANOS3 Control Peptide - AP30583CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Nanos3 Peptide - 4653P from ProSci Category Peptide Species Human

NANOS3 fusion protein - ag17029 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

NANOS3 fusion protein - Ag16014 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human NANOS3 - NANOS3-879H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Nanos homolog 3(NANOS3) - CSB-YP015438HU CSB-EP015438HU CSB-BP015438HU CSB-MP015438HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Nanos3 Protein - NBP2-38011PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

NANOS3 Peptide, Human - M34GP10115H from Creative Peptides Category Peptide Source Synthetic. Species Human

NOS3 Peptide, Human - M34GP10511H from Creative Peptides Category Peptide Source Synthetic. Species Human

Nanos homolog 3 (NANOS3), Recombinant Protein - MBS958545 from MyBioSource Category Protein Prices $920.00, $920.00, $1,140.00, $1,140.00, $1,360.00, $1,360.00, $1,815.00, $1,815.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

eNOS peptide - orb339580 from Biorbyt Category Peptide

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