NANOS3

Gene Symbol NANOS3
Entrez Gene 342977
Alt Symbol NANOS1L, NOS3
Species Human
Gene Type protein-coding
Description nanos homolog 3 (Drosophila)
Other Description nanos homolog 3
Swissprots Q495E5 P60323
Accessions P60323 BC101209 AAI01210 BC101210 AAI01211 BI793167 CK821051 CK821052 DN993610 XM_011527964 XP_011526266 NM_001098622 NP_001092092
Function Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax- dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis. {ECO:0000269|PubMed:21421998}.
Subcellular Location Nucleus {ECO:0000269|PubMed:21421998}. Cytoplasm {ECO:0000269|PubMed:21421998}. Cytoplasmic granule {ECO:0000250}. Cytoplasm, P-body {ECO:0000250}. Note=The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with PUM2, EIF2S1 and TIAL1 in the stress granules. Colocalizes with DCP1A in the P-body (By similarity). {ECO:0000250}.
Tissue Specificity Ovary, testis and brain (at protein level). In the ovaries, expressed during multiple stages of oogenesis, including primordial, primary, secondary and antral follicles with the highest expression in the oocytes. In the testis, expressed in germ cells, type A spermatogonia (SA), primary spermatocytes (S1), round spermatids (S3) and elongated spermatids. {ECO:0000269|PubMed:21421998}.

Nanos3 (A-15) - sc-69191 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nanos3 (A-15): sc-69191. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing cytoplasmic and nuclear staining of cells in seminiferous ducts and cytoplasmic staining of Leydig cells.

Anti-Nanos3 antibody - ab70001 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Nanos3 antibody (ab70001) at 2 µg/ml + Human brain tissue lysate at 15 µg

Anti-NANOS3 / NOS-3 Antibody (Biotin) - LS-C211472 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NANOS3 / NOS-3 Antibody (FITC) - LS-C211473 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NANOS3 / NOS-3 Antibody (HRP) - LS-C211474 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NANOS3 / NOS-3 Antibody - LS-C211475 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NANOS3 / NOS-3 Antibody (C-Terminus) - LS-C53325 from LifeSpan Bioscience

Prices $325.00, $890.00
Sizes 50 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot of Bst2 in Daudi cell lysate with Bst2 antibody at (A) 1 and (B) 2 ug/ml.

Anti-NANOS3 / NOS-3 Antibody (C-Terminus) IHC-plus™ - LS-B4983 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-NANOS3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4983 concentration 5 ug/ml.

Nanos3 Antibody - NBP1-76919 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Nanos3 Antibody [NBP1-76919] - Human brain tissue lysate with Nanos3 antibody at 2 ug/mL.

Nanos3 Antibody - NBP2-38011 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Nanos3 Antibody [NBP2-38011] - Staining of human testis shows strong nuclear positivity in cells in seminiferus ducts and Leydig cells.

Nanos3 Antibody (4B11) - H00342977-M02-100ug from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B11

Nanos3 Polyclonal Antibody - bs-10227R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Mouse heart lysate probed with Rabbit Anti-Nanos3 Polyclonal Antibody, Unconjugated (bs-10227R) at 1:300 in 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:5000 for 90min at 37˚C.

Anti-NANOS3 antibody produced in rabbit - SAB2900839 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NANOS3 (Internal), antibody produced in rabbit: <B>Cat. No. SAB2900839</B>: Anti-NANOS3 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 μg/mL.

Monoclonal Anti-NANOS3 antibody produced in mouse - SAB1412954 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B11
<B>Immunoblotting</B><BR/>Anti-NANOS3:<B>Cat. No. SAB1412954</B>: Antibody concentration: 1 μg/mL. Immunofluorescence band of ~36.7 kDa using immunogen protein lysate.

Anti-Nanos3 antibody produced in rabbit - PRS4653 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Nanos3: <B>Cat. No. PRS4653</B> Western blot analysis of Nanos3 in human brain tissue lysate with Nanos3 antibody at 2 μg/mL.

Nanos3 antibody - GTX85389 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-Nanos3 antibody used in Western blot. GTX85389

eNOS antibody - 10R-1872 from Fitzgerald

Prices $345.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6H2

NANOS3 Polyclonal Antibody - A3577 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal

NOS3 antibody (PE-Cy5.5) - orb130556 from Biorbyt

Prices $425.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal

NOS3 antibody (Alkaline Phosphatase) - orb113791 from Biorbyt

Prices $425.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal

NOS3 antibody (Gold) - orb124293 from Biorbyt

Prices $425.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal

eNOS antibody - 70R-14249 from Fitzgerald

Prices $295.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

NANOS3 antibody - 70R-18746 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

NANOS3 Antibody - abx002588 from Abbexa

Host Rabbit
Clonality Polyclonal

NOS3 (phospho-Ser1177) Antibody - abx000468 from Abbexa

Host Rabbit
Clonality Polyclonal
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