NANOS3

Gene Symbol	NANOS3
Entrez Gene	342977
Alt Symbol	NANOS1L, NOS3
Species	Human
Gene Type	protein-coding
Description	nanos homolog 3 (Drosophila)
Other Description	nanos homolog 3
Swissprots	Q495E5 P60323
Accessions	P60323 BC101209 AAI01210 BC101210 AAI01211 BI793167 CK821051 CK821052 DN993610 XM_011527964 XP_011526266 NM_001098622 NP_001092092
Function	Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax- dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis. {ECO:0000269|PubMed:21421998}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:21421998}. Cytoplasm {ECO:0000269|PubMed:21421998}. Cytoplasmic granule {ECO:0000250}. Cytoplasm, P-body {ECO:0000250}. Note=The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with PUM2, EIF2S1 and TIAL1 in the stress granules. Colocalizes with DCP1A in the P-body (By similarity). {ECO:0000250}.
Tissue Specificity	Ovary, testis and brain (at protein level). In the ovaries, expressed during multiple stages of oogenesis, including primordial, primary, secondary and antral follicles with the highest expression in the oocytes. In the testis, expressed in germ cells, type A spermatogonia (SA), primary spermatocytes (S1), round spermatids (S3) and elongated spermatids. {ECO:0000269|PubMed:21421998}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NOS3 ELISA Kit - abx152537 from Abbexa Category ELISA Kit Sensitivity 5.7 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Nitric oxide synthase, endothelial, NOS3, Human, ELISA Kit - E0815h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 78-5000 pg/mL

Nitric Oxide Synthase 3, Endothelial, NOS3/eNOS, Human, ELISA Kit - E-EL-H0755 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

Nitric Oxide Synthase 3, Endothelial, NOS3/eNOS, Mouse, ELISA Kit - E-EL-M0456 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Nitric Oxide Synthase 3, Endothelial, NOS3/eNOS, Rat, ELISA Kit - E-EL-R0367 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Nitric Oxide Synthase 3, Endothelial, NOS3/eNOS, Rabbit, ELISA Kit - E-EL-RB0340 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Nitric Oxide Synthase 3, Endothelial, NOS3/eNOS, Chicken, ELISA Kit - E-EL-Ch1313 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Nitric Oxide Synthase 3, Endothelial, NOS3/eNOS, Porcine, ELISA Kit - E-EL-P1202 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 7.5 Range 12.5-800pg/mL

Nitric Oxide Synthase 3, Endothelial, NOS3/eNOS, Sheep, ELISA Kit - E-EL-S0432 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Nitric Oxide Synthase 3, Endothelial, NOS3/eNOS, Guinea Pig, ELISA Kit - E-EL-GP0015 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Nitric Oxide Synthase 3, Endothelial, NOS3/eNOS, Monkey, ELISA Kit - E-EL-MK0412 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human NOS3/eNOS(Nitric Oxide Synthase 3, Endothelial) ELISA Kit - E-EL-H0755 from Elabscience Category ELISA Kit Sensitivity 37.50 pg/mL Range 62.50—4000 pg/mL

Human NOS3/eNOS (Nitric Oxide Synthase 3, Endothelial) CLIA Kit - E-CL-H0543 from Elabscience Category CLIA Kit Sensitivity 9.38 pg/mL Range Average Recovery (%)

nanos homolog 3 (Drosophila) , ELISA Kit - MBS9327693 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phospho-eNOS Antibody Duo (Total, pY1177) - ARG30247 from Arigo Biolaboratories Category Antibody Pair

Human NOS3/eNOS (Nitric Oxide Synthase 3, Endothelial) CLIA Kit - E-CL-H0543 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 37.5pg/mL Range 62.5-4000pg/mL

NOS3/eNOS (Nitric Oxide Synthase 3, Endothelial), CLIA Kit - MBS2532982 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625-1000pg/mL

Human NOS3 ELISA Kit - abx574403 from Abbexa Category ELISA Kit Sensitivity 5.5 pg/ml Range 15.625 pg/ml - 1000 pg/ml

NOS3/eNOS - EKH1108 from Nordic BioSite Sensitivity 37.5pg/ml Range 62.5-4000pg/ml

Human NANOS3 ELISA Kit - E025843 from Biobool Category ELISA Kit

Human NOS3 ELISA Kit - E026622 from Biobool Category ELISA Kit Sensitivity 0.27 IU/ml

Human NOS3/eNOS ELISA Kit - E026790 from Biobool Category ELISA Kit Sensitivity 37.5pg/mL

Human NOS3/eNOS (Nitric Oxide Synthase 3, Endothelial) ELISA Kit - EKE60498 from Biomatik Category ELISA Kit Prices $520.00 Sizes 96 tests Sensitivity 37.5 pg/mL Range 62.5-4000 pg/mL

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