TINF2

Gene Symbol	TINF2
Entrez Gene	26277
Alt Symbol	DKCA3, TIN2
Species	Human
Gene Type	protein-coding
Description	TERF1 (TRF1)-interacting nuclear factor 2
Other Description	TERF1-interacting nuclear factor 2|TRF1-interacting nuclear protein 2
Swissprots	Q9UHC2 Q9H904 Q9BSI4 B3W5Q7
Accessions	EAW66048 EAW66049 EAW66050 Q9BSI4 AF195512 AAF18439 AK023166 BAB14440 AK225379 AK294119 BAG57452 AK315084 BC005030 AAH05030 BC019343 AAH19343 BM549897 BX161478 CAD61933 DA053760 DQ893390 ABM84316 DQ896711 ABM87710 EU851975 ACF17559 XM_005267528 XP_005267585 XM_005267529 XP_005267586 XM_011536642 XP_011534944 NM_001099274 NP_001092744 NM_012461 NP_036593
Function	Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix. {ECO:0000269|PubMed:16166375, ECO:0000269|PubMed:16880378}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:19279399}. Chromosome, telomere {ECO:0000269|PubMed:19279399}. Note=Associated with telomeres.
Tissue Specificity	Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-TINF2-cDNA-Clone - DC01595 from Abgent, a WuXi AppTec company Prices $225.00 Sizes 10 µg Species Human

TINF2 - MBS1275963 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC005030

Human TINF2 Gene cDNA clone plasmid - HG14907-G from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14907-ACG from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14907-CF from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid - HG14907-UT from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14907-ANG from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14907-NM from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14907-NY from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14907-CM from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid, N-His tag - HG14907-NH from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid, C-His tag - HG14907-CH from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14907-CY from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14907-ACR from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14907-ANR from Sino Biological Species Human

Human TINF2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14907-NF from Sino Biological Species Human

Human TINF2 ORF Clone(NM_001099274.1) - CDCR346792 from Creative biogene Species Human

human TINF2 ORF clone (NM_012461.2) - CDCH090242 from Creative biogene Species Human

Human TINF2 ORF Clone (BC005030) - CDCS407466 from Creative biogene Species Human Accession Q9BSI4

Human TINF2 ORF clone (BC005030) - CDCB158666 from Creative biogene Species Human

Human TINF2 cDNA Clone(NM_001099274.1) - CDFH019644 from Creative biogene Species Human

Human TINF2 Gene cDNA Clone - orb145533 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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