TINF2

Gene Symbol	TINF2
Entrez Gene	26277
Alt Symbol	DKCA3, TIN2
Species	Human
Gene Type	protein-coding
Description	TERF1 (TRF1)-interacting nuclear factor 2
Other Description	TERF1-interacting nuclear factor 2|TRF1-interacting nuclear protein 2
Swissprots	Q9UHC2 Q9H904 Q9BSI4 B3W5Q7
Accessions	EAW66048 EAW66049 EAW66050 Q9BSI4 AF195512 AAF18439 AK023166 BAB14440 AK225379 AK294119 BAG57452 AK315084 BC005030 AAH05030 BC019343 AAH19343 BM549897 BX161478 CAD61933 DA053760 DQ893390 ABM84316 DQ896711 ABM87710 EU851975 ACF17559 XM_005267528 XP_005267585 XM_005267529 XP_005267586 XM_011536642 XP_011534944 NM_001099274 NP_001092744 NM_012461 NP_036593
Function	Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix. {ECO:0000269|PubMed:16166375, ECO:0000269|PubMed:16880378}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:19279399}. Chromosome, telomere {ECO:0000269|PubMed:19279399}. Note=Associated with telomeres.
Tissue Specificity	Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Tin2 peptide - ab73165 from Abcam Category Peptide

Human Tin2 protein fragment - ab153274 from Abcam Category Protein Source Wheat germ Species Human

TINF2 Antibody Blocking Peptide - LS-E25944 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TIN2 Protein - H00026277-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TINF2 Blocking Peptide - 33R-8348 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TIN2 Blocking Peptide - abx063807 from Abbexa Category Peptide Species Human

TINF2 / TIN2 - H00026277-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TINF2 / TIN2 - H00026277-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TIN2 fusion protein - ag1922 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant TERF1 Interacting Nuclear Factor 2 (TINF2) - RPM366Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

TIN2 Blocking Peptide - CBP2613 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

TIN2 (V94) Peptide - BS2132P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant TERF1 Interacting Nuclear Factor 2 (TINF2) - RPM366Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human TERF1-interacting nuclear factor 2(TINF2) - CSB-YP874799HU CSB-EP874799HU CSB-BP874799HU CSB-MP874799HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TINF2 Protein - abx163790 from Abbexa Category Protein Species Human

TERF1-interacting nuclear factor 2 (TINF2), Recombinant Protein - MBS1470669 from MyBioSource Category Protein Prices $1,230.00, $1,230.00, $1,450.00, $1,450.00, $1,995.00, $1,995.00, $2,460.00, $2,460.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

TINF2 Peptide, Human - M34GP15975H from Creative Peptides Category Peptide Source Synthetic. Species Human

TIN2 Recombinant Protein Antigen - NBP2-56834PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TIN2 Recombinant Protein Antigen - NBP2-55709PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TINF2 peptide - orb218476 from Biorbyt Category Peptide Species Human

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