TINF2

Gene Symbol TINF2
Entrez Gene 26277
Alt Symbol DKCA3, TIN2
Species Human
Gene Type protein-coding
Description TERF1 (TRF1)-interacting nuclear factor 2
Other Description TERF1-interacting nuclear factor 2|TRF1-interacting nuclear protein 2
Swissprots Q9UHC2 Q9H904 Q9BSI4 B3W5Q7
Accessions EAW66048 EAW66049 EAW66050 Q9BSI4 AF195512 AAF18439 AK023166 BAB14440 AK225379 AK294119 BAG57452 AK315084 BC005030 AAH05030 BC019343 AAH19343 BM549897 BX161478 CAD61933 DA053760 DQ893390 ABM84316 DQ896711 ABM87710 EU851975 ACF17559 XM_005267528 XP_005267585 XM_005267529 XP_005267586 XM_011536642 XP_011534944 NM_001099274 NP_001092744 NM_012461 NP_036593
Function Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix. {ECO:0000269|PubMed:16166375, ECO:0000269|PubMed:16880378}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19279399}. Chromosome, telomere {ECO:0000269|PubMed:19279399}. Note=Associated with telomeres.
Tissue Specificity Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

TIN2 CRISPR/Cas9 KO Plasmid (h) - sc-404636 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIN2 HDR Plasmid (h) - sc-404636-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIN2 Double Nickase Plasmid (h) - sc-404636-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIN2 Double Nickase Plasmid (h2) - sc-404636-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIN2 CRISPR Activation Plasmid (h) - sc-404636-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIN2 CRISPR Activation Plasmid (h2) - sc-404636-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIN2 Lentiviral Activation Particles (h) - sc-404636-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIN2 Lentiviral Activation Particles (h2) - sc-404636-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIN2 siRNA (h) - sc-38552 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIN2 shRNA Plasmid (h) - sc-38552-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIN2 shRNA (h) Lentiviral Particles - sc-38552-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIN2 RNAi - H00026277-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN21373 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21373 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06766 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06766

TINF2 siRNA (Human) - CRH8799 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TINF2 - MBS8227049 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TIN2 CRISPR/Cas9 KO Plasmid (h2) - sc-404636-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIN2 HDR Plasmid (h2) - sc-404636-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human TINF2(NM_012461.2) - SHL065136 from Creative biogene

Category siRNA
Species Reactivities Human

Human TINF2 siRNA - orb269301 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TINF2 shRNA Plasmid (Human) - CHH8799 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TINF2 miRNA 3'UTR clone - MiUTR1H-10419 from Creative biogene

Species Reactivities Human

TINF2 miRNA 3'UTR clone - MiUTR3H-06712 from Creative biogene

Species Reactivities Human
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