TINF2

Gene Symbol TINF2
Entrez Gene 26277
Alt Symbol DKCA3, TIN2
Species Human
Gene Type protein-coding
Description TERF1 (TRF1)-interacting nuclear factor 2
Other Description TERF1-interacting nuclear factor 2|TRF1-interacting nuclear protein 2
Swissprots Q9UHC2 Q9H904 Q9BSI4 B3W5Q7
Accessions EAW66048 EAW66049 EAW66050 Q9BSI4 AF195512 AAF18439 AK023166 BAB14440 AK225379 AK294119 BAG57452 AK315084 BC005030 AAH05030 BC019343 AAH19343 BM549897 BX161478 CAD61933 DA053760 DQ893390 ABM84316 DQ896711 ABM87710 EU851975 ACF17559 XM_005267528 XP_005267585 XM_005267529 XP_005267586 XM_011536642 XP_011534944 NM_001099274 NP_001092744 NM_012461 NP_036593
Function Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix. {ECO:0000269|PubMed:16166375, ECO:0000269|PubMed:16880378}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19279399}. Chromosome, telomere {ECO:0000269|PubMed:19279399}. Note=Associated with telomeres.
Tissue Specificity Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

TIN2 (L-15) - sc-13645 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TIN2 (4H262) - sc-73177 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

TIN2 (59B388) - sc-52960 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-Tin2 antibody - ab64386 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Tin2 antibody (ab64386) at 1 µg/mlLane 1 : Thymus (Rat) Tissue LysateLane 2 : Spleen (Mouse) Whole Cell Lysate - normal tissue (ab7937)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-Tin2 antibody - ab82998 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Tin2 antibody (ab82998) at 1 µg/ml (in 5% skim milk / PBS buffer) + MCF7 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Tin2 antibody - ab136997 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Tin2 antibody (ab136997) at 1/500 dilution + HeLa cell lysate at 30 µg

Anti-Tin2 antibody [59B388] - ab13791 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 59B388
All lanes : Anti-Tin2 antibody [59B388] (ab13791) at 2 µg/mlLane 1 : Daudi cell lysateLane 2 : 3T3 cell lysate

Anti-Tin2 antibody [EPR15319] - ab197894 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15319
All lanes : Anti-Tin2 antibody [EPR15319] (ab197894) at 1/10000 dilutionLane 1 : MCF7 (Human breast adenocarcinoma cell line) whole cell lysateLane 2 : WI38 (Human fetal lung fibroblast cells) whole cell lysateLane 3 : HUVEC (Human umbilical vein endothelial cell line) whole cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-TINF2 Antibody (aa44-58) - LS-C92836 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-TINF2 Antibody (Val94) - LS-C176832 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of TIN2 (V94) pAb in extracts from HUVEC cells.

Anti-TINF2 Antibody (C-Terminus) - LS-C102768 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TINF2 antibody LS-C102768 Western blot of MCF7 cell lysate.

Anti-TINF2 Antibody (aa71-120) - LS-C119234 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HUVEC cells, using TINF2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-TINF2 Antibody (aa341-354) IHC-plus™ - LS-B5124 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-TINF2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5124 concentration 3.75 ug/ml.

Anti-TINF2 Antibody (aa45-94) - LS-C200787 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HeLa cells using TINF2 antibody.

Anti-Tin / Tin-2 Antibody (aa44-58, clone 59B388.1) - LS-C597 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 59B388.1
Western blot of Tin2 in Daudi cell lysate using antibody at 2 ug/ml.

TIN2 Antibody (59B388.1) - NB600-1522 from Novus Biologicals

Prices $99.00, $299.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 59B388.1
Western Blot: TIN2 Antibody (59B388.1) [NB600-1522] - Analysis of Tin2 using Tin2 monoclonal antibody 59B388.1. Human Daudi (A) and mouse NIH 3T3 lysate probed using Tin2 antibody at 2 ug/ml.

TIN2 Antibody - NBP1-54837 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TIN2 Antibody - H00026277-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

TIN2 Antibody - NBP1-68139 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: TIN2 Antibody [NBP1-68139] - Analysis of extracts from HuvEc cells, using TIN2 Antibody. The lane on the right is treated with the synthesized peptide.

TIN2 Antibody - NB100-92401 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

TIN2 Antibody (3G11) - H00026277-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G11
Sandwich ELISA: TIN2 Antibody (3G11) [H00026277-M02] - Detection limit for recombinant GST tagged TINF2 is 0.1 ng/ml as a capture antibody.

TIN2 Antibody - H00026277-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

TIN2 Antibody (59B388.1) [Azide Free] - NBP2-33251 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 59B388.1

TIN2 Antibody (59B388.1) [Alexa Fluor (R) 700] - NB600-1522AF700 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 59B388.1

TIN2 Antibody (59B388.1) [Alexa Fluor (R) 647] - NB600-1522AF647 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone 59B388.1
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