PLEKHF2

Gene Symbol	PLEKHF2
Entrez Gene	79666
Alt Symbol	EAPF, PHAFIN2, ZFYVE18
Species	Human
Gene Type	protein-coding
Description	pleckstrin homology domain containing, family F (with FYVE domain) member 2
Other Description	PH and FYVE domain-containing protein 2|PH domain-containing family F member 2|endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains|pleckstrin homology domain-containing family F member 2|zinc finger FYVE domain-containing protein 18
Swissprots	Q9H8W4
Accessions	EAW91743 Q9H8W4 AA767886 AF434819 AAL30774 AK023249 BAB14486 AL834473 CAD39132 AM392581 CAL37459 AM393625 CAL38501 BC011806 AAH11806 DQ893409 ABM84335 DQ896728 ABM87727 NM_024613 NP_078889
Function	May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467). {ECO:0000269|PubMed:18288467, ECO:0000269|PubMed:19995552, ECO:0000269|PubMed:22816767}.
Subcellular Location	Early endosome membrane; Peripheral membrane protein. Endoplasmic reticulum. Note=Colocalizes with EEA1 and RAB5 at endosomal membrane fusion hot spots. May translocate to the endoplasmic reticulum in the early phase of apoptosis (PubMed:18288467). {ECO:0000269|PubMed:18288467}.
Tissue Specificity	Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells. {ECO:0000269|PubMed:18288467}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PLEKHF2 full length protein - ab164068 from Abcam Category Protein Source Wheat germ Species Human

Human PLEKHF2 full length protein - ab177709 from Abcam Category Protein Source E. coli Species Human

PLEKHF2 Antibody Blocking Peptide - LS-E4500 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PLEKHF2 Antibody Blocking Peptide - LS-E18299 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PLEKHF2 Recombinant Protein - H00079666-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

PLEKHF2-Antibody-Center-Blocking-Peptide - BP16820c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PLEKHF2 protein (His tag) - 80R-3701 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

PLEKHF2 (1-249, His-tag) - AR51388PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

PLEKHF2 (1-249, His-tag) - AR51388PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

PLEKHF2 - H00079666-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PLEKHF2 - H00079666-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PLEKHF2, 1-249aa Human, His tag, E.coli - 01-P2568 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Recombinant Human PLEKHF2, His-tagged - PLEKHF2-5072H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human pleckstrin homology domain containing, family F (with FYVE domain) member 2, His-tagged - PLEKHF2-471H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Pleckstrin homology domain-containing family F member 2(PLEKHF2) - CSB-YP884492HU CSB-EP884492HU CSB-BP884492HU CSB-MP884492HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PLEKHF2, 1-249aa, Human, His tag, E.coli - ATGP2568 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

PLEKHF2 Protein - abx163426 from Abbexa Category Protein Species Human, Mouse, Rat

PLEKHF2 - TP303964 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Pleckstrin homology domain-containing family F member 2 (PLEKHF2), Recombinant Protein - MBS1452953 from MyBioSource Category Protein Prices $1,000.00, $1,000.00, $1,230.00, $1,230.00, $1,530.00, $1,530.00, $1,995.00, $1,995.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 1 mg (E-Coli), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PLEKHF2, Recombinant Protein - MBS205520 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 100 µg, 500 µg Source E Coli Species Human

PLEKHF2 Recombinant Protein Antigen - NBP1-82265PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PLEKHF2 Peptide, Human - M34GP11933H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human PLEKHF2 protein - orb260018 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

PLEKHF2 Recombinant Protein - NBP2-51582 from Novus Biologicals Category Protein Prices $259.00 Sizes 100 µg Source E. coli Species Human

PLEKHF2 - PAT-82567-1 from Nordic BioSite Category Protein Species Human

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