PLEKHF2

Gene Symbol PLEKHF2
Entrez Gene 79666
Alt Symbol EAPF, PHAFIN2, ZFYVE18
Species Human
Gene Type protein-coding
Description pleckstrin homology domain containing, family F (with FYVE domain) member 2
Other Description PH and FYVE domain-containing protein 2|PH domain-containing family F member 2|endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains|pleckstrin homology domain-containing family F member 2|zinc finger FYVE domain-containing protein 18
Swissprots Q9H8W4
Accessions EAW91743 Q9H8W4 AA767886 AF434819 AAL30774 AK023249 BAB14486 AL834473 CAD39132 AM392581 CAL37459 AM393625 CAL38501 BC011806 AAH11806 DQ893409 ABM84335 DQ896728 ABM87727 NM_024613 NP_078889
Function May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467). {ECO:0000269|PubMed:18288467, ECO:0000269|PubMed:19995552, ECO:0000269|PubMed:22816767}.
Subcellular Location Early endosome membrane; Peripheral membrane protein. Endoplasmic reticulum. Note=Colocalizes with EEA1 and RAB5 at endosomal membrane fusion hot spots. May translocate to the endoplasmic reticulum in the early phase of apoptosis (PubMed:18288467). {ECO:0000269|PubMed:18288467}.
Tissue Specificity Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells. {ECO:0000269|PubMed:18288467}.

PLEKHF2 (C-17) - sc-87358 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PLEKHF2 antibody - ab127047 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PLEKHF2 antibody (ab127047) at 1/500 dilutionLane 1 : Jurkat whole cell lysateLane 2 : Raji whole cell lysateLysates/proteins at 30 µg per lane.

Anti-PLEKHF2 antibody - ab56098 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLEKHF2 Antibody (aa71-98) - LS-C163788 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PLEKHF2 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The PLEKHF2 antibody detected the PLEKHF2 protein (arrow).

Anti-PLEKHF2 Antibody - LS-C155569 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Breast ca, using PLEKHF2 antibody at 1:500 dilution.

Anti-PLEKHF2 Antibody (N-Terminus) - LS-C47041 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLEKHF2 Antibody (aa71-98, AP) - LS-C266536 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHF2 Antibody (aa71-98, Biotin) - LS-C266538 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHF2 Antibody (aa71-98, APC) - LS-C266537 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHF2 Antibody (aa71-98, FITC) - LS-C266539 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHF2 Antibody (aa71-98, Azide-free, HRP) - LS-C266541 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHF2 Antibody (aa71-98, PE) - LS-C284631 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHF2 Antibody (aa70-98) - LS-C324103 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHF2 Antibody (N-Terminus) - LS-C146266 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PLEKHF2 antibody LS-C146266 Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml.

PLEKHF2 Antibody - NBP1-82265 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PLEKHF2 Antibody [NBP1-82265] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY411203)

PLEKHF2 Antibody - NBP2-19865 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PLEKHF2 Antibody [NBP2-19865] - Sample (30 ug of whole cell lysate) A: Jurkat B: Raji 12% SDS PAGE gel, diluted at 1:500.

PLEKHF2 Antibody - H00079666-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: PLEKHF2 Antibody [H00079666-B01] - analysis of PLEKHF2 expression in transfected 293T cell line by PLEKHF2 MaxPab polyclonal antibody (B01). Lane 1: PLEKHF2 transfected lysate (27.80 KDa). Lane 2: Non-transfected lysate.

ANTI-PLEKHF2 (CENTER) antibody produced in rabbit - SAB1304413 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PLEKHF2 (Center): <B>Cat. No. SAB1304413</B>: PLEKHF2 Antibody (Center) western blot analysis in HL_60 cell line lysates (35 μg/lane).

Anti-PLEKHF2 antibody produced in rabbit - HPA024829 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PLEKHF2: <B>Cat. No. HPA024829</B>: Immunohistochemical staining of human stomach shows moderate cytoplasmic positivity in glandular cells.

Anti-PLEKHF2 antibody produced in rabbit - SAB2700574 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PLEKHF2: <B>Cat. No. SAB2700574</B>: Immunohistochemical analysis of paraffin-embedded Breast carcinoma, using PLEKHF2 antibody at 1:500 dilution.

PLEKHF2-Antibody-Center - AP16820c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
PLEKHF2 Antibody (Center) (Cat. #AP16820c) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PLEKHF2 antibody detected the PLEKHF2 protein (arrow).

PLEKHF2 Antibody - middle region (OAAB12235) - OAAB12235 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

PLEKHF2 Antibody - abx029090 from Abbexa

Host Rabbit
Clonality Polyclonal

PLEKHF2 (Center) antibody - AP53349PU-N from Acris Antibodies

Prices $330.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of PLEKHF2 Antibody (Center) Cat.-No AP53349PU-N in HL-60 cell line lysates (35ug/lane). This demonstrates the PLEKHF2 antibody detected the PLEKHF2 protein (arrow).

PLEKHF2 antibody - H00079666-B01 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of PLEKHF2 expression in transfected 293T cell line (H00079666-T01) by PLEKHF2 MaxPab polyclonal antibody.Lane 1: PLEKH
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