NKD2

Gene Symbol NKD2
Entrez Gene 85409
Alt Symbol Naked2
Species Human
Gene Type protein-coding
Description naked cuticle homolog 2 (Drosophila)
Other Description Dvl-binding protein NKD2|protein naked cuticle homolog 2
Swissprots Q9BSN0 Q96EK8 Q969F2
Accessions EAX08182 EAX08183 EAX08184 Q969F2 AB062887 BAB70501 AF358137 AAK57486 BC004940 AAH04940 BC012176 AAH12176 BE061409 XM_005248382 XP_005248439 XM_005248383 XP_005248440 XM_006725007 XP_006725070 XM_006725009 XP_006725072 XM_011514150 XP_011512452 XM_011546475 XP_011544777 NM_001271082 NP_001258011 NM_033120 NP_149111
Function Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity (By similarity). Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells. {ECO:0000250, ECO:0000269|PubMed:15064403, ECO:0000269|PubMed:17553928}.
Subcellular Location Cell membrane. Cytoplasm. Cytoplasmic vesicle.
Tissue Specificity Expressed in kidney, lung, pancreas and spleen. {ECO:0000269|PubMed:11604995}.
Top Pathways Wnt signaling pathway

NKD2 293T Cell Transient Overexpression Lysate(Denatured) - H00085409-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

NKD2 overexpression lysate - LY409725 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

NKD2 Overexpression Lysate (Denatured) - H00085409-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

NKD2 Overexpression Lysate (Native) - NBP2-05917 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: NKD2 Overexpression Lysate (Adult Normal) [NBP2-05917] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NKD2.

Panoply™ Human NKD2 Knockdown Stable Cell Line - CSC-DC010402 from Creative biogene

Category Cell Line
Species Human
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