Gene Symbol | NKD2 |
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Entrez Gene | 85409 |
Alt Symbol | Naked2 |
Species | Human |
Gene Type | protein-coding |
Description | naked cuticle homolog 2 (Drosophila) |
Other Description | Dvl-binding protein NKD2|protein naked cuticle homolog 2 |
Swissprots | Q9BSN0 Q96EK8 Q969F2 |
Accessions | EAX08182 EAX08183 EAX08184 Q969F2 AB062887 BAB70501 AF358137 AAK57486 BC004940 AAH04940 BC012176 AAH12176 BE061409 XM_005248382 XP_005248439 XM_005248383 XP_005248440 XM_006725007 XP_006725070 XM_006725009 XP_006725072 XM_011514150 XP_011512452 XM_011546475 XP_011544777 NM_001271082 NP_001258011 NM_033120 NP_149111 |
Function | Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity (By similarity). Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells. {ECO:0000250, ECO:0000269|PubMed:15064403, ECO:0000269|PubMed:17553928}. |
Subcellular Location | Cell membrane. Cytoplasm. Cytoplasmic vesicle. |
Tissue Specificity | Expressed in kidney, lung, pancreas and spleen. {ECO:0000269|PubMed:11604995}. |
Top Pathways | Wnt signaling pathway |
Human NKD2 full length protein - ab164753 from Abcam
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NKD2 Antibody Blocking Peptide - LS-E1452 from LifeSpan Bioscience
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NKD2 Antibody Blocking Peptide - LS-E26524 from LifeSpan Bioscience
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NKD2 Antibody Blocking Peptide - LS-E15185 from LifeSpan Bioscience
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Recombinant Human NKD2 Protein - H00085409-P01 from Novus Biologicals
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NKD2-Antibody-C-term-Blocking-peptide - BP12158b from Abgent, a WuXi AppTec company
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NKD2 blocking peptide - GTX88932-PEP from GeneTex
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NKD2 Blocking Peptide - 33R-1463 from Fitzgerald
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NKD2 Peptide - AC21-1360-P from Abcore
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NKD2 - H00085409-P01-10 from Acris Antibodies
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NKD2 - H00085409-P01-25 from Acris Antibodies
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NKD2 Peptide - 45-969P from ProSci
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Naked2 fusion protein - ag10094 from Proteintech Group
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Naked2 fusion protein - ag9818 from Proteintech Group
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Recombinant Human Protein naked cuticle homolog 2(NKD2) - CSB-YP822162HU CSB-EP822162HU CSB-BP822162HU CSB-MP822162HU from Cusabio
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NKD2, Peptide - MBS425749 from MyBioSource
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NKD2 Protein - NBP2-13658PEP from Novus Biologicals
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NKD2 Peptide, Human - M34GP10402H from Creative Peptides
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Protein naked cuticle homolog 2 (NKD2), Recombinant Protein - MBS1404829 from MyBioSource
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