Gene Symbol | NKD2 |
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Entrez Gene | 85409 |
Alt Symbol | Naked2 |
Species | Human |
Gene Type | protein-coding |
Description | naked cuticle homolog 2 (Drosophila) |
Other Description | Dvl-binding protein NKD2|protein naked cuticle homolog 2 |
Swissprots | Q9BSN0 Q96EK8 Q969F2 |
Accessions | EAX08182 EAX08183 EAX08184 Q969F2 AB062887 BAB70501 AF358137 AAK57486 BC004940 AAH04940 BC012176 AAH12176 BE061409 XM_005248382 XP_005248439 XM_005248383 XP_005248440 XM_006725007 XP_006725070 XM_006725009 XP_006725072 XM_011514150 XP_011512452 XM_011546475 XP_011544777 NM_001271082 NP_001258011 NM_033120 NP_149111 |
Function | Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity (By similarity). Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells. {ECO:0000250, ECO:0000269|PubMed:15064403, ECO:0000269|PubMed:17553928}. |
Subcellular Location | Cell membrane. Cytoplasm. Cytoplasmic vesicle. |
Tissue Specificity | Expressed in kidney, lung, pancreas and spleen. {ECO:0000269|PubMed:11604995}. |
Top Pathways | Wnt signaling pathway |
Naked2 (C36D3) Rabbit mAb - 2596 from Cell Signaling Technology
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Naked2 (C67C4) Rabbit mAb - 2073 from Cell Signaling Technology
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NKD2 (Q-14) - sc-163143 from Santa Cruz Biotechnology
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NKD2 (S-15) - sc-163144 from Santa Cruz Biotechnology
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NKD2 (N-14) - sc-163142 from Santa Cruz Biotechnology
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NKD2 (L-24) - sc-133824 from Santa Cruz Biotechnology
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Anti-NKD2 antibody - ab67911 from Abcam
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Anti-NKD2 antibody - ab169144 from Abcam
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Anti-NKD2 antibody - C-terminal - ab170804 from Abcam
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Anti-NKD2 Antibody (aa382-394) - LS-C55178 from LifeSpan Bioscience
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Anti-NKD2 Antibody (Gly47) - LS-C73161 from LifeSpan Bioscience
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Anti-NKD2 Antibody (aa366-393, AP) - LS-C223472 from LifeSpan Bioscience
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Anti-NKD2 Antibody (aa366-393, Biotin) - LS-C223473 from LifeSpan Bioscience
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Anti-NKD2 Antibody (aa366-393, APC) - LS-C223474 from LifeSpan Bioscience
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Anti-NKD2 Antibody (aa366-393, FITC) - LS-C223475 from LifeSpan Bioscience
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Anti-NKD2 Antibody (aa366-393, Azide-free, HRP) - LS-C223476 from LifeSpan Bioscience
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Anti-NKD2 Antibody (aa366-393, PE) - LS-C223477 from LifeSpan Bioscience
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Anti-NKD2 Antibody (aa373-401) - LS-C323348 from LifeSpan Bioscience
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Anti-NKD2 Antibody (aa43-92) - LS-C30341 from LifeSpan Bioscience
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Anti-NKD2 Antibody (aa366-393) - LS-C164889 from LifeSpan Bioscience
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NKD2 Antibody - NBP2-13658 from Novus Biologicals
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NKD2 Antibody - NBP1-54733 from Novus Biologicals
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NKD2 Antibody - H00085409-B01P from Novus Biologicals
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NKD2 Antibody - NBP1-06058 from Novus Biologicals
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NKD2 Antibody - H00085409-A01 from Novus Biologicals
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