NKD2

Gene Symbol NKD2
Entrez Gene 85409
Alt Symbol Naked2
Species Human
Gene Type protein-coding
Description naked cuticle homolog 2 (Drosophila)
Other Description Dvl-binding protein NKD2|protein naked cuticle homolog 2
Swissprots Q9BSN0 Q96EK8 Q969F2
Accessions EAX08182 EAX08183 EAX08184 Q969F2 AB062887 BAB70501 AF358137 AAK57486 BC004940 AAH04940 BC012176 AAH12176 BE061409 XM_005248382 XP_005248439 XM_005248383 XP_005248440 XM_006725007 XP_006725070 XM_006725009 XP_006725072 XM_011514150 XP_011512452 XM_011546475 XP_011544777 NM_001271082 NP_001258011 NM_033120 NP_149111
Function Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity (By similarity). Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells. {ECO:0000250, ECO:0000269|PubMed:15064403, ECO:0000269|PubMed:17553928}.
Subcellular Location Cell membrane. Cytoplasm. Cytoplasmic vesicle.
Tissue Specificity Expressed in kidney, lung, pancreas and spleen. {ECO:0000269|PubMed:11604995}.
Top Pathways Wnt signaling pathway

Naked2 (C36D3) Rabbit mAb - 2596 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C36D3
Western blot analysis of COS cell extracts, untransfected or transiently transfected with a construct expressing mouse Naked2, using Naked2 (C36D3) Rabbit mAb.

Naked2 (C67C4) Rabbit mAb - 2073 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C67C4
Western blot analysis of extracts from various cell lines using Naked2 (C67C4) Rabbit mAb.

NKD2 (Q-14) - sc-163143 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NKD2 (S-15) - sc-163144 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NKD2 (N-14) - sc-163142 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NKD2 (N-14): sc-163142. Western blot analysis of NKD2 expression in Jurkat (A), HEK293 (B), MOLT-4 (C) and HCT-116 (D) whole cell lysates.

NKD2 (L-24) - sc-133824 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
NKD2 (L-24): sc-133824. Western blot analysis of NKD2 expression in Jurkat whole cell lysate.

Anti-NKD2 antibody - ab67911 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-NKD2 antibody (ab67911) at 1/500 dilutionLane 1 : NKD2 transfected 293T cell lysateLane 2 : non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

Anti-NKD2 antibody - ab169144 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NKD2 antibody (ab169144) at 1 µg/mlLane 1 : NKD2 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgG (H+L) at 1/7500 dilution

Anti-NKD2 antibody - C-terminal - ab170804 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Flow cytometric analysis of Jurkat cells labeling NKD2 using ab170804 at a 1/10 dilution (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used.

Anti-NKD2 Antibody (aa382-394) - LS-C55178 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-NKD2 Antibody (Gly47) - LS-C73161 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal

Anti-NKD2 Antibody (aa366-393, AP) - LS-C223472 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKD2 Antibody (aa366-393, Biotin) - LS-C223473 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKD2 Antibody (aa366-393, APC) - LS-C223474 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKD2 Antibody (aa366-393, FITC) - LS-C223475 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKD2 Antibody (aa366-393, Azide-free, HRP) - LS-C223476 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKD2 Antibody (aa366-393, PE) - LS-C223477 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKD2 Antibody (aa373-401) - LS-C323348 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NKD2 Antibody (aa43-92) - LS-C30341 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Jurkat Cell Lysate

Anti-NKD2 Antibody (aa366-393) - LS-C164889 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
NKD2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

NKD2 Antibody - NBP2-13658 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NKD2 Antibody [NBP2-13658] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp.  Lane 4: Human plasma (IgG/HSA depleted).  Lane 5: Human liver tissue

NKD2 Antibody - NBP1-54733 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NKD2 Antibody [NBP1-54733] - Jurkat cell lysate, concentration 0.2-1 ug/ml.

NKD2 Antibody - H00085409-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: NKD2 Antibody [H00085409-B01P] - Analysis of NKD2 expression in transfected 293T cell line by NKD2 polyclonal antibody.  Lane 1: NKD2 transfected lysate(34.21 KDa). Lane 2: Non-transfected lysate.

NKD2 Antibody - NBP1-06058 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

NKD2 Antibody - H00085409-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
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