Gene Symbol | NCS1 |
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Entrez Gene | 23413 |
Alt Symbol | FLUP, FREQ |
Species | Human |
Gene Type | protein-coding |
Description | neuronal calcium sensor 1 |
Other Description | frequenin homolog|frequenin-like protein|frequenin-like ubiquitous protein |
Swissprots | Q9UK26 E9PAY3 P62166 P36610 |
Accessions | EAW87926 EAW87927 P62166 AF134479 AAP97256 AF186409 AAF01804 AI521726 AI564128 AI768193 AK023889 AK024709 AL161981 BC004856 AAH04856 BC008698 BM011362 BQ880305 BU150740 CF453730 CK301145 DA092531 X84048 CAA58867 NM_001128826 NP_001122298 NM_014286 NP_055101 |
Function | Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N- type voltage-gated calcium channel (By similarity). {ECO:0000250}. |
Subcellular Location | Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cytoplasm, perinuclear region. Cell membrane; Peripheral membrane protein. Note=Associated with Golgi stacks. Post-synaptic densities of dendrites, and in the pre-synaptic nerve terminal at neuromuscular junctions. |
Human NCS1 full length protein - ab183224 from Abcam
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Human NCS1 full length protein - ab95349 from Abcam
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Human NCS1 full length protein - ab116417 from Abcam
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NCS1 / Neuronal Calcium Sensor Antibody Blocking Peptide - LS-E3396 from LifeSpan Bioscience
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NCS1 / Neuronal Calcium Sensor Antibody Blocking Peptide - LS-E3814 from LifeSpan Bioscience
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NCS1 / Neuronal Calcium Sensor Antibody Blocking Peptide - LS-E12348 from LifeSpan Bioscience
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Frequenin Recombinant Protein - H00023413-P01 from Novus Biologicals
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Recombinant Human Frequenin Protein - NBP1-44484 from Novus Biologicals
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Frequenin Peptide - P0564 from Novus Biologicals
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FREQ-Antibody-N-term-Blocking-Peptide - BP14572a from Abgent, a WuXi AppTec company
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NCS1-Antibody-Center-Blocking-Peptide - BP1551c from Abgent, a WuXi AppTec company
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NCS1 Protein (OPPA02335) - OPPA02335 from Aviva Systems Biology
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Human NCS1 protein - orb81231 from Biorbyt
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NCS1 Blocking Peptide - 33R-10882 from Fitzgerald
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NCS1 protein (His tag) - 80R-1291 from Fitzgerald
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NCS1 protein (His tag) - 80R-3940 from Fitzgerald
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FREQ / Frequenin homolog - H00023413-P01-02 from Acris Antibodies
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NCS1 (1-190, His-tag) - AR09426PU-L from Acris Antibodies
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NCS1 (1-190, His-tag) - AR09426PU-N from Acris Antibodies
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NCS1 (1-190, His-tag) - AR51627PU-N from Acris Antibodies
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NCS1 (1-190, His-tag) - AR51627PU-S from Acris Antibodies
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Neuronal Calcium Sensor 1, Human Recombinant - 228-13243-1 from RayBiotech
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Recombinant Human Neuronal Calcium Sensor 1 - 228-13243-2 from RayBiotech
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Recombinant Human Neuronal Calcium Sensor 1 - 228-13243-3 from RayBiotech
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NCS1, 1- 190 aa, Human, His-tagged, Recombinant, E.coli - 01-1811-1 from ARP American Research Products
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