NCS1

Gene Symbol NCS1
Entrez Gene 23413
Alt Symbol FLUP, FREQ
Species Human
Gene Type protein-coding
Description neuronal calcium sensor 1
Other Description frequenin homolog|frequenin-like protein|frequenin-like ubiquitous protein
Swissprots Q9UK26 E9PAY3 P62166 P36610
Accessions EAW87926 EAW87927 P62166 AF134479 AAP97256 AF186409 AAF01804 AI521726 AI564128 AI768193 AK023889 AK024709 AL161981 BC004856 AAH04856 BC008698 BM011362 BQ880305 BU150740 CF453730 CK301145 DA092531 X84048 CAA58867 NM_001128826 NP_001122298 NM_014286 NP_055101
Function Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N- type voltage-gated calcium channel (By similarity). {ECO:0000250}.
Subcellular Location Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cytoplasm, perinuclear region. Cell membrane; Peripheral membrane protein. Note=Associated with Golgi stacks. Post-synaptic densities of dendrites, and in the pre-synaptic nerve terminal at neuromuscular junctions.

NCS-1 CRISPR/Cas9 KO Plasmid (h) - sc-404303 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCS-1 HDR Plasmid (h) - sc-404303-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCS-1 Double Nickase Plasmid (h) - sc-404303-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCS-1 Double Nickase Plasmid (h2) - sc-404303-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCS-1 CRISPR Activation Plasmid (h) - sc-404303-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCS-1 CRISPR Activation Plasmid (h2) - sc-404303-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCS-1 Lentiviral Activation Particles (h) - sc-404303-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCS-1 Lentiviral Activation Particles (h2) - sc-404303-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NCS-1 siRNA (h) - sc-36019 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NCS-1 shRNA Plasmid (h) - sc-36019-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NCS-1 shRNA (h) Lentiviral Particles - sc-36019-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Frequenin RNAi - H00023413-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU049011 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15115 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15115 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR14107 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr14107

NCS1 siRNA (Human) - CRH8252 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NCS1 (NM_014286.3) - SHH350232 from Creative biogene

Category siRNA
Species Reactivities Human

Human NCS1 siRNA - orb268754 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NCS1 shRNA Plasmid (Human) - CHH8252 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NCS1 miRNA 3'UTR clone - MiUTR4H-TG05896 from Creative biogene

Species Reactivities Human
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