Gene Symbol | LRIG1 |
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Entrez Gene | 26018 |
Alt Symbol | LIG-1, LIG1 |
Species | Human |
Gene Type | protein-coding |
Description | leucine-rich repeats and immunoglobulin-like domains 1 |
Other Description | leucine-rich repeat protein LRIG1|leucine-rich repeats and immunoglobulin-like domains protein 1|ortholog of mouse integral membrane glycoprotein LIG-1 |
Swissprots | Q9BYB8 Q96JA1 Q6IQ51 Q9UFI4 Q96CF9 |
Accessions | EAW65452 EAW65453 Q96JA1 AB050468 BAB40659 AF381545 AAK62357 AK126745 BAG54369 AK294984 BAH11940 AK314103 AL117666 CAB56036 AY730707 AAU44786 BC014276 AAH14276 BC071561 AAH71561 BC140907 AAI40908 XM_011533578 XP_011531880 XM_011533579 XP_011531881 NM_015541 NP_056356 |
Function | Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation. {ECO:0000269|PubMed:15282549}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:11414704}; Single-pass type I membrane protein {ECO:0000269|PubMed:11414704}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:11414704}. |
DNA ligase 1, LIG1, Human, ELISA Kit - E9137h from ARP American Research Products
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Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1), Human, ELISA Kit - CSB-EL013084HU from ARP American Research Products
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Human Leucine-rich repeats and immunoglobulin-like domains protein 1(LRIG1) ELIS - CSB-EL013084HU from Cusabio
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leucine-rich repeats and immunoglobulin-like domains 1, ELISA Kit - MBS908302 from MyBioSource
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Custom Human LRIG1 ELISA - ELH-LRIG1-1 from RayBiotech
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Human LIG1 ELISA Kit - E012136 from Biobool
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Human LRIG1 ELISA Kit - E022531 from Biobool
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LRIG1 ELISA Kit (Human) (OKCA00711) - OKCA00711 from Aviva Systems Biology
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anti-LIG1 antibody - ARG55337 from Arigo Biolaboratories
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anti-LIG1 / DNA ligase I antibody - ARG64962 from Arigo Biolaboratories
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Custom Human LRIG1 ELISA Kit - orb384646 from Biorbyt
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