USP25

Gene Symbol	USP25
Entrez Gene	29761
Alt Symbol	USP21
Species	Human
Gene Type	protein-coding
Description	ubiquitin specific peptidase 25
Other Description	USP on chromosome 21|deubiquitinating enzyme 25|ubiquitin carboxyl-terminal hydrolase 25|ubiquitin thioesterase 25|ubiquitin thiolesterase 25|ubiquitin-specific processing protease 25
Swissprots	Q9H9W1 Q9UHP3 Q6DHZ9 C0LSZ0
Accessions	EAX10041 EAX10042 EAX10043 EAX10044 EAX10045 Q9UHP3 AF134213 AAF24998 AF170562 AAF32263 AK022447 BAB14037 AK022574 BAB14107 AK094083 BC015930 AAH15930 BC018686 BC075792 AAH75792 BI256537 BM149594 BQ215557 FJ763652 ACN76567 HG765100 CDJ98632 XM_005260949 XP_005261006 XM_006723992 XP_006724055 XM_011529529 XP_011527831 XM_011529530 XP_011527832 XM_011529531 XP_011527833 XM_011529532 XP_011527834 XM_011529533 XP_011527835 XM_011529534 XP_011527836 XM_011529535 XP_011527837 NM_001283041 NP_001269970 NM_001283042 NP_001269971 NM_013396 NP_037528
Function	Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:16501887, ECO:0000269|PubMed:19440361}.
Tissue Specificity	Isoform USB25a is found in most adult and fetal tissues; expression is moderately high in testis, pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, but very low in peripheral blood, colon, small intestine, ovary, prostate, thymus and spleen. Isoform USB25b is found in all tissues except heart and skeletal muscle. Isoform USB25m is heart and skeletal muscle specific. {ECO:0000269|PubMed:10644437, ECO:0000269|PubMed:11597335}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

USP25-Over-expression-Lysate - LY14669a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

USP25 overexpression lysate - LY415616 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

USP25 293 Cell Lysate - 407344 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

USP25 Overexpression Lysate (Native) - NBL1-17654 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

USP25 Over-expression Lysate Product - GWB-9A6A2C from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Panoply™ Human USP25 Knockdown Stable Cell Line - CSC-DC017168 from Creative biogene Category Cell Line Species Human

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