USP25

Gene Symbol	USP25
Entrez Gene	29761
Alt Symbol	USP21
Species	Human
Gene Type	protein-coding
Description	ubiquitin specific peptidase 25
Other Description	USP on chromosome 21|deubiquitinating enzyme 25|ubiquitin carboxyl-terminal hydrolase 25|ubiquitin thioesterase 25|ubiquitin thiolesterase 25|ubiquitin-specific processing protease 25
Swissprots	Q9H9W1 Q9UHP3 Q6DHZ9 C0LSZ0
Accessions	EAX10041 EAX10042 EAX10043 EAX10044 EAX10045 Q9UHP3 AF134213 AAF24998 AF170562 AAF32263 AK022447 BAB14037 AK022574 BAB14107 AK094083 BC015930 AAH15930 BC018686 BC075792 AAH75792 BI256537 BM149594 BQ215557 FJ763652 ACN76567 HG765100 CDJ98632 XM_005260949 XP_005261006 XM_006723992 XP_006724055 XM_011529529 XP_011527831 XM_011529530 XP_011527832 XM_011529531 XP_011527833 XM_011529532 XP_011527834 XM_011529533 XP_011527835 XM_011529534 XP_011527836 XM_011529535 XP_011527837 NM_001283041 NP_001269970 NM_001283042 NP_001269971 NM_013396 NP_037528
Function	Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:16501887, ECO:0000269|PubMed:19440361}.
Tissue Specificity	Isoform USB25a is found in most adult and fetal tissues; expression is moderately high in testis, pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, but very low in peripheral blood, colon, small intestine, ovary, prostate, thymus and spleen. Isoform USB25b is found in all tissues except heart and skeletal muscle. Isoform USB25m is heart and skeletal muscle specific. {ECO:0000269|PubMed:10644437, ECO:0000269|PubMed:11597335}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human USP25 full length protein - ab188736 from Abcam Category Protein Prices $572.00 Sizes 50 µg Source Baculovirus infected Sf21 cells Species Human

Human USP25 full length protein - ab157024 from Abcam Category Protein Source E. coli Species Human

Human USP25 full length protein - ab131968 from Abcam Category Protein Source Wheat germ Species Human

Human USP25 protein fragment - ab127242 from Abcam Category Protein Source E. coli Species Human

USP25 Antibody Blocking Peptide - LS-E6899 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP25 Antibody Blocking Peptide - LS-E6900 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

USP25 Recombinant Protein - H00029761-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

USP25 Peptide - P0952 from Novus Biologicals Category Peptide Species Human

USP25 Peptide - P0951 from Novus Biologicals Category Peptide Species Human

USP25-Antibody-C-term-Blocking-Peptide - BP2150b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP25-Antibody-N-term-Blocking-Peptide - BP2150a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human His6-USP25, CF - E-546-050 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived, Contains a C-terminal 6-His tag

USP25 - H00029761-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

USP25 - H00029761-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

USP25 Peptide - 7765P from ProSci Category Peptide Species Human

USP25 fusion protein - Ag2837 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human USP25, GST-tagged - USP25-3623H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human USP25, GST-tagged - USP25-187H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 25(USP25) ,partial - CSB-YP883400HU CSB-EP883400HU CSB-BP883400HU CSB-MP883400HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human His6-USP25 Protein, CF - E-546 from R&D Systems Category Protein Prices $249.00 Sizes 50 µg Source Spodoptera frugiperda , Sf 21 (baculovirus)-derived Contains a C-terminal 6-His tag Species Human

USP25 Protein - abx164502 from Abbexa Category Protein Species Human, Mouse, Rat

USP25 - TP309755 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

USP25 Recombinant Protein Antigen - NBP1-80631PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

USP25 Recombinant Protein Antigen - NBP1-80630PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

USP25 Peptide, Human - M34GP17168H from Creative Peptides Category Peptide Source Synthetic. Species Human

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