USP25

Gene Symbol USP25
Entrez Gene 29761
Alt Symbol USP21
Species Human
Gene Type protein-coding
Description ubiquitin specific peptidase 25
Other Description USP on chromosome 21|deubiquitinating enzyme 25|ubiquitin carboxyl-terminal hydrolase 25|ubiquitin thioesterase 25|ubiquitin thiolesterase 25|ubiquitin-specific processing protease 25
Swissprots Q9H9W1 Q9UHP3 Q6DHZ9 C0LSZ0
Accessions EAX10041 EAX10042 EAX10043 EAX10044 EAX10045 Q9UHP3 AF134213 AAF24998 AF170562 AAF32263 AK022447 BAB14037 AK022574 BAB14107 AK094083 BC015930 AAH15930 BC018686 BC075792 AAH75792 BI256537 BM149594 BQ215557 FJ763652 ACN76567 HG765100 CDJ98632 XM_005260949 XP_005261006 XM_006723992 XP_006724055 XM_011529529 XP_011527831 XM_011529530 XP_011527832 XM_011529531 XP_011527833 XM_011529532 XP_011527834 XM_011529533 XP_011527835 XM_011529534 XP_011527836 XM_011529535 XP_011527837 NM_001283041 NP_001269970 NM_001283042 NP_001269971 NM_013396 NP_037528
Function Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16501887, ECO:0000269|PubMed:19440361}.
Tissue Specificity Isoform USB25a is found in most adult and fetal tissues; expression is moderately high in testis, pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, but very low in peripheral blood, colon, small intestine, ovary, prostate, thymus and spleen. Isoform USB25b is found in all tissues except heart and skeletal muscle. Isoform USB25m is heart and skeletal muscle specific. {ECO:0000269|PubMed:10644437, ECO:0000269|PubMed:11597335}.

USP25 CRISPR/Cas9 KO Plasmid (h) - sc-406674 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP25 HDR Plasmid (h) - sc-406674-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP25 Double Nickase Plasmid (h) - sc-406674-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP25 Double Nickase Plasmid (h2) - sc-406674-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP25 CRISPR Activation Plasmid (h) - sc-406674-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP25 CRISPR Activation Plasmid (h2) - sc-406674-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP25 Lentiviral Activation Particles (h) - sc-406674-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP25 Lentiviral Activation Particles (h2) - sc-406674-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

USP25 siRNA (h) - sc-76829 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

USP25 shRNA Plasmid (h) - sc-76829-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

USP25 shRNA (h) Lentiviral Particles - sc-76829-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU092431 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22573 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22573 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

USP25 siRNA (Human) - CRH9218 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

USP25 - MBS8203781 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human USP25 (NM_013396.3) - SHH441396 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human USP25(NM_013396.3) - SHL117378 from Creative biogene

Category siRNA
Species Reactivities Human

USP25 shRNA Plasmid (Human) - CHH9218 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

USP25 miRNA 3'UTR clone - MiUTR1H-11054 from Creative biogene

Species Reactivities Human
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