USP25

Gene Symbol	USP25
Entrez Gene	29761
Alt Symbol	USP21
Species	Human
Gene Type	protein-coding
Description	ubiquitin specific peptidase 25
Other Description	USP on chromosome 21|deubiquitinating enzyme 25|ubiquitin carboxyl-terminal hydrolase 25|ubiquitin thioesterase 25|ubiquitin thiolesterase 25|ubiquitin-specific processing protease 25
Swissprots	Q9H9W1 Q9UHP3 Q6DHZ9 C0LSZ0
Accessions	EAX10041 EAX10042 EAX10043 EAX10044 EAX10045 Q9UHP3 AF134213 AAF24998 AF170562 AAF32263 AK022447 BAB14037 AK022574 BAB14107 AK094083 BC015930 AAH15930 BC018686 BC075792 AAH75792 BI256537 BM149594 BQ215557 FJ763652 ACN76567 HG765100 CDJ98632 XM_005260949 XP_005261006 XM_006723992 XP_006724055 XM_011529529 XP_011527831 XM_011529530 XP_011527832 XM_011529531 XP_011527833 XM_011529532 XP_011527834 XM_011529533 XP_011527835 XM_011529534 XP_011527836 XM_011529535 XP_011527837 NM_001283041 NP_001269970 NM_001283042 NP_001269971 NM_013396 NP_037528
Function	Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:16501887, ECO:0000269|PubMed:19440361}.
Tissue Specificity	Isoform USB25a is found in most adult and fetal tissues; expression is moderately high in testis, pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, but very low in peripheral blood, colon, small intestine, ovary, prostate, thymus and spleen. Isoform USB25b is found in all tissues except heart and skeletal muscle. Isoform USB25m is heart and skeletal muscle specific. {ECO:0000269|PubMed:10644437, ECO:0000269|PubMed:11597335}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

USP25 (H-140) - sc-367503 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

USP25 (C-17) - sc-79308 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

USP25 (C-5) - sc-398414 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

USP25 (D-18) - sc-79309 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-USP25 antibody - ab191703 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-USP25 antibody - ab38498 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-USP25 antibody - ab124422 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-USP25 antibody - ab38500 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-USP25 antibody - ab5092 from Abcam Prices $235.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-USP25 antibody [1277CT376106171] - ab188362 from Abcam Prices $370.00 Sizes 400 µl Host Mouse Clonality Monoclonal Clone 1277CT376106171

Anti-USP25 antibody [EPR15019] - ab187156 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR15019

Anti-USP25 Antibody (Internal) IHC-plus™ - LS-B12060 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (N-Terminus, APC) - LS-C226655 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (N-Terminus, AP) - LS-C226656 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (N-Terminus, Biotin) - LS-C226657 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (N-Terminus, FITC) - LS-C226658 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (N-Terminus, Azide-free, HRP) - LS-C226659 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (N-Terminus, PE) - LS-C226660 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (C-Terminus, AP) - LS-C226661 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (C-Terminus, APC) - LS-C226662 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (C-Terminus, FITC) - LS-C226664 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (C-Terminus, Biotin) - LS-C226663 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (C-Terminus, Azide-free, HRP) - LS-C226665 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (C-Terminus, PE) - LS-C226666 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-USP25 Antibody (N-Terminus) - LS-C329069 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

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