KDM7A

Gene Symbol	KDM7A
Entrez Gene	80853
Alt Symbol	JHDM1D
Species	Human
Gene Type	protein-coding
Description	lysine (K)-specific demethylase 7A
Other Description	histone lysine demethylase JHDM1D|jmjC domain-containing histone demethylation protein 1D|jumonji C domain containing histone demethylase 1 homolog D|jumonji C domain-containing histone demethylase 1 homolog D|lysine-specific demethylase 7|lysine-specific demethylase 7A
Swissprots	C9JQU2 Q9C0E5 Q6MZL8 A4D1S9 C9JJH9 Q6ZMT4
Accessions	AAS00360 EAL24032 EAW83940 Q6ZMT4 AB051505 BAB21809 AK057208 AK131497 BAD18641 BC127007 AAI27008 BX641017 CAE46011 BX649115 XM_011516586 XP_011514888 XM_011516587 XP_011514889 NM_030647 NP_085150
Function	Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate. {ECO:0000269|PubMed:20023638, ECO:0000269|PubMed:20194436, ECO:0000269|PubMed:20622853}.
Subcellular Location	Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human JHDM1D peptide - ab36042 from Abcam Category Peptide

Human JHDM1D peptide - ab36043 from Abcam Category Peptide

Human JHDM1D peptide - ab37903 from Abcam Category Peptide

Human JHDM1D peptide - ab37904 from Abcam Category Peptide

KDM7A / JHDM1D Antibody Blocking Peptide - LS-E7742 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

JHDM1D-Antibody-Center-Blocking-Peptide - BP5116c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

JHDM1D Blocking Peptide - 33R-4837 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Recombinant JHDM1D-l protein - 31464 from ActiveMotif Category Protein Prices $425.00 Sizes 20 µg Source E. coli Species Human

Recombinant JHDM1D-s protein - 31463 from ActiveMotif Category Protein Prices $425.00 Sizes 20 µg Source E. coli Species Human

Recombinant Human JHDM1D, GST-tagged - JHDM1D-46H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human JHDM1D - JHDM1D-47H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Lysine-specific demethylase 7(JHDM1D) ,partial - CSB-YP747775HU CSB-EP747775HU CSB-BP747775HU CSB-MP747775HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

KDM7A Protein - abx163514 from Abbexa Category Protein Species Human, Mouse, Rat

JHDM1D Recombinant Protein Antigen - NBP1-81382PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

JHDM1D Peptide, Human - M34GP07860H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant KDM7A protein - 31576 from ActiveMotif Category Protein Prices $395.00 Sizes 10 µg Source Baculovirus Species Human

Lysine-specific demethylase 7 (JHDM1D), partial, Recombinant Protein - MBS1343911 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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