KLHL22

Gene Symbol KLHL22
Entrez Gene 84861
Alt Symbol KELCHL
Species Human
Gene Type protein-coding
Description kelch-like family member 22
Other Description kelch-like 22|kelch-like protein 22
Swissprots B7Z2G1 A8MTV3 D3DX30 A8K3Q4 Q53GT1 Q96KC6 Q96B68
Accessions EAX02961 EAX02962 EAX02963 EAX02964 Q53GT1 AK024369 AK027266 BAB55007 AK222850 BAD96570 AK290669 BAF83358 AK294682 BAH11847 BC015923 AAH15923 CR456352 CAG30238 CU013062 CAK54493 CU013350 CAK54792 DA381792 XM_011530469 XP_011528771 NM_032775 NP_116164 NR_033825
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation. {ECO:0000269|PubMed:19995937, ECO:0000269|PubMed:23455478}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:23455478}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:23455478}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:23455478}. Note=Mainly. cytoplasmic in prophase and prometaphase. Associates with the mitotic spindle as the cells reach chromosome bi-orientation. Localizes to the centrosomes shortly before cells enter anaphase After anaphase onset, predominantly associates with the polar microtubules connecting the 2 opposing centrosomes and gradually diffuses into the cytoplasm during telophase.

kelch-like 22 (Drosophila) , ELISA Kit - MBS9330249 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ng/ml.
Range 6.25 ng/ml - 200 ng/ml.

Human KLHL22 ELISA Kit - E087748 from Biobool

Category ELISA Kit

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9381602 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9372280 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9379575 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9373685 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9378154 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9375620 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9381889 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9377006 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9370618 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9381508 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9376081 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9379312 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9375070 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9379026 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9374646 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9379944 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9376922 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9377512 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9371105 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Kelch-Like Protein 22 (KLHL22), ELISA Kit - MBS9377220 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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