MBL2

Gene Symbol	MBL2
Entrez Gene	4153
Alt Symbol	COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD
Species	Human
Gene Type	protein-coding
Description	mannose-binding lectin (protein C) 2, soluble
Other Description	collectin-1|mannan-binding lectin|mannose-binding lectin (protein C) 2, soluble (opsonic defect)|mannose-binding lectin 2, soluble (opsonic defect)|mannose-binding protein C
Swissprots	Q4VB12 Q96KE4 Q86SI4 Q96TF8 Q96TF7 Q4VB13 P11226 Q4VB14 Q96TF9 Q5SQS3
Accessions	AAC31937 AAN39274 AAN39275 ABB01009 ACA48258 ACC62880 ACE06983 BAB17020 CAA34079 CAB56044 CAB56045 CAB56120 CAB56121 CAB56122 CAB56123 CAB56124 CAJ58412 CCE53522 CCE67084 CCE67089 CCE67094 CCF12075 CCQ77659 CCQ77665 CCQ77670 CDH61700 EAW54148 EAW54149 P11226 AF360991 AAK52907 AY826184 AAV80468 BC069338 AAH69338 BC096179 AAH96179 BC096180 AAH96180 BC096181 AAH96181 BC096182 AAH96182 X15422 CAA33462 XM_006717861 XP_006717924 XM_011539816 XP_011538118 NM_000242 NP_000233
Function	Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. {ECO:0000269|PubMed:14515269}.
Subcellular Location	Secreted {ECO:0000269|PubMed:7982896}.
Tissue Specificity	Plasma protein produced mainly in the liver. {ECO:0000269|PubMed:18006063}.
Top Pathways	Complement and coagulation cascades, Phagosome, Staphylococcus aureus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MBL-C (H-50) - sc-25615 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

MBL-C (N-14) - sc-17908 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

MBL-C (HYB 131-01) - sc-59299 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

MBL-C (3B6) - sc-80595 from Santa Cruz Biotechnology Prices $279.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

Anti-Mannan Binding Lectin antibody - ab203303 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Mannan Binding Lectin antibody - ab103251 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Mannan Binding Lectin antibody - ab102593 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Mannan Binding Lectin antibody - ab137259 from Abcam Prices $376.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Mannan Binding Lectin antibody - ab31296 from Abcam Prices $376.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-Mannan Binding Lectin antibody [11C9] - ab26277 from Abcam Prices $378.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 11C9

Anti-Mannan Binding Lectin antibody [11F11] - ab23461 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 11F11

Anti-Mannan Binding Lectin antibody [15C5] - ab23460 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 15C5

Anti-Mannan Binding Lectin antibody [1E2] - ab23458 from Abcam Prices $376.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1E2

Anti-Mannan Binding Lectin antibody [3B6] - ab23457 from Abcam Prices $391.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3B6

Anti-Mannan Binding Lectin antibody [EPSISR5] - ab133629 from Abcam Prices $385.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPSISR5

Anti-Mannan Binding Lectin antibody [EPSISR5] - ab150426 from Abcam Prices $379.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPSISR5

Anti-Mannan Binding Lectin antibody [MM0464-4J25] - ab89570 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Monoclonal Clone MM0464-4J25

Anti-Mannan Binding Lectin antibody - Aminoterminal end - ab56127 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-MBL2 / Mannose Binding Protein Antibody - LS-C25384 from LifeSpan Bioscience Prices $445.00 Sizes 100 µl Host Mouse Clonality Monoclonal

Anti-MBL2 / Mannose Binding Protein Antibody - LS-C25385 from LifeSpan Bioscience Prices $515.00 Sizes 200 µg Host Mouse Clonality Monoclonal

Anti-MBL2 / Mannose Binding Protein Antibody - LS-C25386 from LifeSpan Bioscience Host Mouse Clonality Monoclonal

Anti-MBL2 / Mannose Binding Protein Antibody - LS-C25387 from LifeSpan Bioscience Prices $485.00 Sizes 200 µg Host Mouse Clonality Monoclonal

Anti-MBL2 / Mannose Binding Protein Antibody - LS-C25389 from LifeSpan Bioscience Prices $710.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-MBL2 / Mannose Binding Protein Antibody - LS-C25391 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-MBL2 / Mannose Binding Protein Antibody - LS-C25392 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Mouse Clonality Monoclonal

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