MBL2

Gene Symbol MBL2
Entrez Gene 4153
Alt Symbol COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD
Species Human
Gene Type protein-coding
Description mannose-binding lectin (protein C) 2, soluble
Other Description collectin-1|mannan-binding lectin|mannose-binding lectin (protein C) 2, soluble (opsonic defect)|mannose-binding lectin 2, soluble (opsonic defect)|mannose-binding protein C
Swissprots Q4VB12 Q96KE4 Q86SI4 Q96TF8 Q96TF7 Q4VB13 P11226 Q4VB14 Q96TF9 Q5SQS3
Accessions AAC31937 AAN39274 AAN39275 ABB01009 ACA48258 ACC62880 ACE06983 BAB17020 CAA34079 CAB56044 CAB56045 CAB56120 CAB56121 CAB56122 CAB56123 CAB56124 CAJ58412 CCE53522 CCE67084 CCE67089 CCE67094 CCF12075 CCQ77659 CCQ77665 CCQ77670 CDH61700 EAW54148 EAW54149 P11226 AF360991 AAK52907 AY826184 AAV80468 BC069338 AAH69338 BC096179 AAH96179 BC096180 AAH96180 BC096181 AAH96181 BC096182 AAH96182 X15422 CAA33462 XM_006717861 XP_006717924 XM_011539816 XP_011538118 NM_000242 NP_000233
Function Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. {ECO:0000269|PubMed:14515269}.
Subcellular Location Secreted {ECO:0000269|PubMed:7982896}.
Tissue Specificity Plasma protein produced mainly in the liver. {ECO:0000269|PubMed:18006063}.
Top Pathways Complement and coagulation cascades, Phagosome, Staphylococcus aureus infection

MBL-C CRISPR/Cas9 KO Plasmid (h) - sc-403131 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBL-C HDR Plasmid (h) - sc-403131-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBL-C Double Nickase Plasmid (h) - sc-403131-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBL-C Double Nickase Plasmid (h2) - sc-403131-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBL-C CRISPR Activation Plasmid (h) - sc-403131-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBL-C CRISPR Activation Plasmid (h2) - sc-403131-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBL-C Lentiviral Activation Particles (h) - sc-403131-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBL-C Lentiviral Activation Particles (h2) - sc-403131-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MBL-C siRNA (h) - sc-35869 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MBL-C shRNA Plasmid (h) - sc-35869-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MBL-C shRNA (h) Lentiviral Particles - sc-35869-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MBL RNAi - H00004153-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU041811 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13083 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13083 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MBL2 siRNA (Human) - CRH2826 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MBL2 (NM_000242.2) - SHH338867 from Creative biogene

Category siRNA
Species Reactivities Human

MBL2 shRNA Plasmid (Human) - CHH2826 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MBL2 miRNA 3'UTR clone - MiUTR4H-TG05397 from Creative biogene

Species Reactivities Human
Search more