MBL2

Gene Symbol MBL2
Entrez Gene 4153
Alt Symbol COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD
Species Human
Gene Type protein-coding
Description mannose-binding lectin (protein C) 2, soluble
Other Description collectin-1|mannan-binding lectin|mannose-binding lectin (protein C) 2, soluble (opsonic defect)|mannose-binding lectin 2, soluble (opsonic defect)|mannose-binding protein C
Swissprots Q4VB12 Q96KE4 Q86SI4 Q96TF8 Q96TF7 Q4VB13 P11226 Q4VB14 Q96TF9 Q5SQS3
Accessions AAC31937 AAN39274 AAN39275 ABB01009 ACA48258 ACC62880 ACE06983 BAB17020 CAA34079 CAB56044 CAB56045 CAB56120 CAB56121 CAB56122 CAB56123 CAB56124 CAJ58412 CCE53522 CCE67084 CCE67089 CCE67094 CCF12075 CCQ77659 CCQ77665 CCQ77670 CDH61700 EAW54148 EAW54149 P11226 AF360991 AAK52907 AY826184 AAV80468 BC069338 AAH69338 BC096179 AAH96179 BC096180 AAH96180 BC096181 AAH96181 BC096182 AAH96182 X15422 CAA33462 XM_006717861 XP_006717924 XM_011539816 XP_011538118 NM_000242 NP_000233
Function Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. {ECO:0000269|PubMed:14515269}.
Subcellular Location Secreted {ECO:0000269|PubMed:7982896}.
Tissue Specificity Plasma protein produced mainly in the liver. {ECO:0000269|PubMed:18006063}.
Top Pathways Complement and coagulation cascades, Phagosome, Staphylococcus aureus infection

MBL2-Over-expression-Lysate - LY10262a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag MBL2 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MBL2 gene (Lane 2, Cat. #LY10262a).

MBL2 overexpression lysate - LY424849 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

MBL2 293 Cell Lysate - 410292 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

MBL Overexpression Lysate (Native) - NBL1-12927 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Mannan Binding Lectin Overexpression Lysate (Adult Normal) [NBL1-12927] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Mannan Binding Lectin.

MBL2 Over-expression Lysate Product - GWB-2C53D8 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Human MBL2 / MBL / COLEC1 CHO Cell Lysate (WB positive control) - 10405-HNASL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Human

Human MBL2 CHO Transfected Lysate (positive control) (denatured) - orb175352 from Biorbyt

Category Cell Lysate
Prices $425.00
Sizes 300 μg
Species Human

Panoply™ Human MBL2 Knockdown Stable Cell Line - CSC-DC009280 from Creative biogene

Category Cell Line
Species Human
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