MBL2

Gene Symbol	MBL2
Entrez Gene	4153
Alt Symbol	COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD
Species	Human
Gene Type	protein-coding
Description	mannose-binding lectin (protein C) 2, soluble
Other Description	collectin-1|mannan-binding lectin|mannose-binding lectin (protein C) 2, soluble (opsonic defect)|mannose-binding lectin 2, soluble (opsonic defect)|mannose-binding protein C
Swissprots	Q4VB12 Q96KE4 Q86SI4 Q96TF8 Q96TF7 Q4VB13 P11226 Q4VB14 Q96TF9 Q5SQS3
Accessions	AAC31937 AAN39274 AAN39275 ABB01009 ACA48258 ACC62880 ACE06983 BAB17020 CAA34079 CAB56044 CAB56045 CAB56120 CAB56121 CAB56122 CAB56123 CAB56124 CAJ58412 CCE53522 CCE67084 CCE67089 CCE67094 CCF12075 CCQ77659 CCQ77665 CCQ77670 CDH61700 EAW54148 EAW54149 P11226 AF360991 AAK52907 AY826184 AAV80468 BC069338 AAH69338 BC096179 AAH96179 BC096180 AAH96180 BC096181 AAH96181 BC096182 AAH96182 X15422 CAA33462 XM_006717861 XP_006717924 XM_011539816 XP_011538118 NM_000242 NP_000233
Function	Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. {ECO:0000269|PubMed:14515269}.
Subcellular Location	Secreted {ECO:0000269|PubMed:7982896}.
Tissue Specificity	Plasma protein produced mainly in the liver. {ECO:0000269|PubMed:18006063}.
Top Pathways	Complement and coagulation cascades, Phagosome, Staphylococcus aureus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MBL (Mannose-Binding Lectin) Human ELISA Kit - ab193709 from Abcam Category ELISA Kit Prices $475.00 Sizes 1 x 96 tests Sensitivity 0.03 ng/ml Range 0.03 ng/ml - 25 ng/ml

Human MBL2 / Mannose Binding Protein ELISA Kit (Sandwich ELISA) - LS-F4698 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.065 ng/ml Range 0.034-8.333 ng/ml

Mouse MBL2 / Mannose Binding Protein ELISA Kit (Sandwich ELISA) - LS-F5805 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.067 ng/ml Range 0.034-8.333 ng/ml

Human MBL2 / Mannose Binding Protein ELISA Kit (Sandwich ELISA) - LS-F145 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 0.034 ng/ml Range 0.034-8.333 ng/ml

Mouse MBL2 / Mannose Binding Protein ELISA Kit (Custom ELISA) - LS-F394 from LifeSpan Bioscience Category ELISA Kit Prices $670.00, $1,190.00, $2,570.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity To be determined Range 0.034-8.333 ng/ml

Human MBL2 / Mannose Binding Protein ELISA Kit (Sandwich ELISA) - LS-F710 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.034-8.333 ng/ml

Chicken MBL2 / Mannose Binding Protein ELISA Kit (Sandwich ELISA) - LS-F9288 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.57 ng/ml Range 0.034-8.333 ng/ml

Human MBL2 / Mannose Binding Protein ELISA Kit - LS-F9444 from LifeSpan Bioscience Category ELISA Kit Prices $1,020.00 Sizes 1 plate Sensitivity 2.77 ng/ml Range 6.25 - 400 ng/ml

Rat MBL2 / Mannose Binding Protein ELISA Kit (Sandwich ELISA) - LS-F9460 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.126 ng/ml Range 0.034-8.333 ng/ml

Human MBL2 / Mannose Binding Protein ELISA Kit (Sandwich ELISA) - LS-F10096 from LifeSpan Bioscience Category ELISA Kit Prices $630.00 Sizes 1 plate Sensitivity 0.171 ng/ml Range 0.034-8.333 ng/ml

Mouse MBL2 / Mannose Binding Protein ELISA Kit (Sandwich ELISA) - LS-F10491 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 0.034-8.333 ng/ml

Human MBL2 / Mannose Binding Protein ELISA Kit (Sandwich ELISA) - LS-F10490 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 0.034-8.333 ng/ml

Human MBL2 / Mannose Binding Protein ELISA Kit (Sandwich ELISA) - LS-F12007 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 0.156 Range 0.034-8.333 ng/ml

Human MBL2 / Mannose-binding Protein C ELISA Kit - RAB0548 from Sigma-Aldrich Category ELISA Kit Prices $633.00 Sizes 1 kt Sensitivity 0.03 ng/mL

Human MBL Quantikine ELISA Kit - DMBL00 from R&D Systems Category ELISA Kit Prices $509.00 Sizes 1 kit Sensitivity 0.029 ng/mL Range 0.2 - 10 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)

Human MBL DuoSet ELISA - DY2307 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 15.60 - 1,000 pg/mL

Quantikine Immunoassay Control Set 839 for Human MBL - QC118 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

MBL ELISA Kit (Human) : 96 Wells (OKAG00235) - OKAG00235 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 16 pg/mL Range 16-1,000 pg/mL

Human Anti-MBL ELISA Kit - abx150685 from Abbexa Category ELISA Kit Sensitivity 2.77 ng/ml Range 6.25 ng/ml - 400 ng/ml

Human Anti-MBP ELISA Kit - abx150686 from Abbexa Category ELISA Kit Sensitivity 0.64 ng/ml Range 1.563 ng/ml - 100 ng/ml

Human MBL ELISA Kit - abx152283 from Abbexa Category ELISA Kit Sensitivity 0.074 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human MBP ELISA Kit - abx054314 from Abbexa Category ELISA Kit

Anti-Mannose Binding Lectin Antibody (Anti-MBL), Human, ELISA Kit - SEK513Hu from ARP American Research Products Category ELISA Kit Prices $1,018.00 Sizes 96 t Sensitivity 1.44ng/mL Range 3.12-200ng/mL

Anti-Myelin Basic Protein Antibody (Anti-MBP), Human, ELISA Kit - SEK509Hu from ARP American Research Products Category ELISA Kit Prices $820.00 Sizes 96 t Sensitivity 0.64ng/mL Range 1.56-100ng/mL

Mannma binding protein/mannan binding lectin, MBP/MBL, Human, ELISA Kit - CSB-E09717h from ARP American Research Products Category ELISA Kit Prices $325.00, $495.00, $496.00, $498.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 7.81 ng/ml Range 31.25 ng/ml-2000 ng/ml

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