MBL2

Gene Symbol	MBL2
Entrez Gene	4153
Alt Symbol	COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD
Species	Human
Gene Type	protein-coding
Description	mannose-binding lectin (protein C) 2, soluble
Other Description	collectin-1|mannan-binding lectin|mannose-binding lectin (protein C) 2, soluble (opsonic defect)|mannose-binding lectin 2, soluble (opsonic defect)|mannose-binding protein C
Swissprots	Q4VB12 Q96KE4 Q86SI4 Q96TF8 Q96TF7 Q4VB13 P11226 Q4VB14 Q96TF9 Q5SQS3
Accessions	AAC31937 AAN39274 AAN39275 ABB01009 ACA48258 ACC62880 ACE06983 BAB17020 CAA34079 CAB56044 CAB56045 CAB56120 CAB56121 CAB56122 CAB56123 CAB56124 CAJ58412 CCE53522 CCE67084 CCE67089 CCE67094 CCF12075 CCQ77659 CCQ77665 CCQ77670 CDH61700 EAW54148 EAW54149 P11226 AF360991 AAK52907 AY826184 AAV80468 BC069338 AAH69338 BC096179 AAH96179 BC096180 AAH96180 BC096181 AAH96181 BC096182 AAH96182 X15422 CAA33462 XM_006717861 XP_006717924 XM_011539816 XP_011538118 NM_000242 NP_000233
Function	Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. {ECO:0000269|PubMed:14515269}.
Subcellular Location	Secreted {ECO:0000269|PubMed:7982896}.
Tissue Specificity	Plasma protein produced mainly in the liver. {ECO:0000269|PubMed:18006063}.
Top Pathways	Complement and coagulation cascades, Phagosome, Staphylococcus aureus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Mannan Binding Lectin full length protein - ab151947 from Abcam Category Protein Source HEK 293 cells Species Human

Human Mannan Binding Lectin peptide (237-248) (Carboxyterminal end) - ab45655 from Abcam Category Peptide Species Human

Human Mannan Binding Lectin protein fragment - ab137143 from Abcam Category Protein Source E. coli Species Human

MBL2 / Mannose Binding Protein Antibody Blocking Peptide - LS-E2661 from LifeSpan Bioscience Category Protein Prices $145.00 Sizes 100 µg

MBL2 / Mannose Binding Protein Antibody Blocking Peptide - LS-E25802 from LifeSpan Bioscience Category Protein Prices $145.00 Sizes 100 µg

MBL2 / Mannose Binding Protein Antibody Blocking Peptide - LS-E16678 from LifeSpan Bioscience Category Protein Prices $145.00 Sizes 100 µg

MBP / Myelin Basic Protein Antibody Blocking Peptide - LS-E20374 from LifeSpan Bioscience Category Protein Prices $145.00 Sizes 100 µg

MBP / Myelin Basic Protein Antibody Blocking Peptide - LS-E20375 from LifeSpan Bioscience Category Protein Prices $145.00 Sizes 100 µg

Recombinant Human MBL Protein - NBP2-23215 from Novus Biologicals Category Protein Prices $299.00 Sizes 100 µg Source E.coli Species Human

Recombinant Bacterial MBP Protein - NBP2-22654 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli

Recombinant Human MBP Protein - NBP2-23253 from Novus Biologicals Category Protein Prices $349.00 Sizes 100 µg Source E.coli Species Human

MBL2-Antibody-C-term-Blocking-peptide - BP13736b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MBL-C blocking peptide - GTX89586-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human MBL - 2307-MB-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Glu21-Ile248

Recombinant Human MBL, CF - 2307-MB-050/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Glu21-Ile248

Human MBL-2 protein (Native) - orb139322 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source CHO Stable Cells Species Human

Human MBL2 protein - orb49530 from Biorbyt Category Protein Prices $272.00, $366.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source HEK293

E. coli MBP protein - orb191304 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Escherichia coli

Human MBP1 protein - orb84744 from Biorbyt Category Protein Prices $417.00, $570.00 Sizes 50 μg, 100 μg Source E. coli Species Human

Human MBL2 protein - orb168790 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human, Guinea pig MBP (87-99) peptide - orb71759 from Biorbyt Category Peptide Prices $400.00 Sizes 5 mg Species Human

MBP (87-99) Human peptide - orb216694 from Biorbyt Category Peptide Prices $230.00, $485.00, $536.00 Sizes 1 mg, 5 mg, 10 mg Species Human

MBL2 Blocking Peptide - 33R-4323 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

MBL2 protein (His tag) - 80R-2590 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

MBP Blocking Peptide - 33R-2903 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

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