CTDSPL

Gene Symbol	CTDSPL
Entrez Gene	10217
Alt Symbol	C3orf8, HYA22, PSR1, RBSP3, SCP3
Species	Human
Gene Type	protein-coding
Description	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
Other Description	CTD small phosphatase-like protein|CTDSP-like|NIF-like protein|NLI-interacting factor 1|RB protein serine phosphatase from chromosome 3|carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3|nuclear LIM interactor-interacting factor 1|small C-terminal domain phosphatase 3|small CTD phosphatase 3
Swissprots	Q7Z5Q2 Q3ZTU0 Q70KI4 O15194
Accessions	EAW64502 EAW64503 EAW64504 EAW64505 O15194 AI143812 AI192993 AJ575644 CAE11804 AJ575645 CAE11805 AY279532 AAP34400 AY364238 AAQ76797 BC166643 AAI66643 D88153 BAA21667 NM_001008392 NP_001008393 NM_005808 NP_005799
Function	Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. {ECO:0000250, ECO:0000269|PubMed:12721286}.
Subcellular Location	Nucleus {ECO:0000250}.
Tissue Specificity	Expression is restricted to non-neuronal tissues. {ECO:0000269|PubMed:15681389}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CTDSPL overexpression lysate - LY401765 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CTDSPL overexpression lysate - LY423419 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CTDSPL 293 Cell Lysate - 409938 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CTDSPL 293 Cell Lysate - 401577 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CTDSPL Overexpression Lysate (Native) - NBP2-08808 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CTDSPL Overexpression Lysate (Native) - NBL1-09569 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CTDSPL Over-expression Lysate Product - GWB-C5299A from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

CTDSPL Over-expression Lysate Product - GWB-327083 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human CTDSPL Knockdown Stable Cell Line - CSC-DC003792 from Creative biogene Category Cell Line Species Human

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