CTDSPL

Gene Symbol CTDSPL
Entrez Gene 10217
Alt Symbol C3orf8, HYA22, PSR1, RBSP3, SCP3
Species Human
Gene Type protein-coding
Description CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
Other Description CTD small phosphatase-like protein|CTDSP-like|NIF-like protein|NLI-interacting factor 1|RB protein serine phosphatase from chromosome 3|carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3|nuclear LIM interactor-interacting factor 1|small C-terminal domain phosphatase 3|small CTD phosphatase 3
Swissprots Q7Z5Q2 Q3ZTU0 Q70KI4 O15194
Accessions EAW64502 EAW64503 EAW64504 EAW64505 O15194 AI143812 AI192993 AJ575644 CAE11804 AJ575645 CAE11805 AY279532 AAP34400 AY364238 AAQ76797 BC166643 AAI66643 D88153 BAA21667 NM_001008392 NP_001008393 NM_005808 NP_005799
Function Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. {ECO:0000250, ECO:0000269|PubMed:12721286}.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Expression is restricted to non-neuronal tissues. {ECO:0000269|PubMed:15681389}.

CTDSPL (H-71) - sc-368678 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CTDSPL (H-71): sc-368678. Western blot analysis of CTDSPL expression in RAW 264.7 (A) and K-562 (B) whole cell lysates, HeLa nuclear extract (C) and mouse liver tissue extract (D).

CTDSPL (N-14) - sc-102463 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

CTDSPL (P-12) - sc-102464 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-CTDSPL antibody - ab105068 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CTDSPL antibody (ab105068) at 1 µg/ml + DLD1 cell lysate at 10 µg

Anti-CTDSPL antibody - ab106973 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CTDSPL antibody (ab106973) at 1/100 dilution + HeLa cell lysate at 35 µg

Anti-CTDSPL / SCP3 Antibody (Internal) - LS-C87271 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal

Anti-CTDSPL / SCP3 Antibody (aa4-34, AP) - LS-C255625 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSPL / SCP3 Antibody (aa4-34, Biotin) - LS-C255629 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSPL / SCP3 Antibody (aa4-34, APC) - LS-C255628 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSPL / SCP3 Antibody (aa4-34, FITC) - LS-C255630 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSPL / SCP3 Antibody (aa4-34, Azide-free, HRP) - LS-C255631 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSPL / SCP3 Antibody (aa4-34, PE) - LS-C255632 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSPL / SCP3 Antibody (aa4-34) - LS-C320662 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSPL / SCP3 Antibody (aa48-97) - LS-C40376 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CTDSPL antibody LS-C40376 IHC of formalin-fixed, paraffin-embedded human Kidney. Positive label: Epithelial cells of renal tubule indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.

Anti-CTDSPL / SCP3 Antibody (aa4-34) - LS-C167124 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CTDSPL Antibody western blot of HeLa cell line lysates (35 ug/lane). The CTDSPL antibody detected the CTDSPL protein (arrow).

SCP3/SYCP3 Antibody (6F9B6) - NBP2-37324 from Novus Biologicals

Prices $369.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6F9B6
Western Blot: SCP3/SYCP3 Antibody (6F9B6) [NBP2-37324] - Western blot analysis using SYCP3 mAb against HEK293 (1) and SYCP3 (AA: 27-128)-hIgGFc transfected HEK293 (2) cell lysate.

CTDSPL Antibody - NBP1-53169 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CTDSPL Antibody - NBP2-31913 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: CTDSPL Antibody [NBP2-31913] - Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.

CTDSPL Antibody - NBP1-20903 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

SCP3 Polyclonal Antibody - bs-3509R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat testis labeled with Anti- SCP3 Polyclonal Antibody, Unconjugated (bs-3509R) at 1:200 followed by secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated (bs-0295G-Cy3) used at 1:200 dilution for 40 minutes at 37°C. DAPI was used to stain the cell nuclei.

CTDSPL Polyclonal Antibody - bs-8241R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CTDSPL antibody produced in rabbit - HPA048325 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CTDSPL: <B>Cat. No. HPA048325</B>: Immunohistochemical staining of Human lung shows moderate membranous positivity in pneumocytes.

Anti-CTDSPL antibody produced in rabbit - AV42261 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CTDSPL: <B>Cat. No. AV42261</B>: Immunohistochemistry of CTDSPL in Human Kidney tissue with CTDSPL antibody at 4-8 μg/mL.

CTDSPL antibody - N-terminal region (ARP42261_P050) - ARP42261_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CTDSPL Antibody - N-terminal region (OAAB00039) - OAAB00039 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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