UNC45A

Gene Symbol UNC45A
Entrez Gene 55898
Alt Symbol GC-UNC45, GCUNC-45, GCUNC45, IRO039700, SMAP-1, SMAP1, UNC-45A
Species Human
Gene Type protein-coding
Description unc-45 homolog A (C. elegans)
Other Description general cell UNC45|protein unc-45 homolog A|smooth muscle cell associated protein-1
Swissprots Q9NSE8 Q9NSE9 A8K6F7 Q9H3U8 Q7L3Y6 Q9H3U1
Accessions EAX02127 EAX02128 EAX02129 Q9H3U1 AB014729 BAB20266 AB014736 BAB20273 AK000905 BAA91418 AK125523 AK125721 BAG54239 AK291622 BAF84311 AK293538 BAG57020 AK296964 BAG59508 AK302979 BAG64122 AL357532 AL357537 CAB93428 AL357538 CAB93429 BC006214 AAH06214 BC010995 AAH10995 BC037992 AAH37992 BC045635 AAH45635 DQ892953 ABM83879 DQ896200 ABM87199 XM_005254963 XP_005255020 XM_011521779 XP_011520081 XM_011521780 XP_011520082 NM_017979 NM_001039675 NP_001034764 NM_018671 NP_061141
Function Acts as co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen (By similarity). {ECO:0000250, ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16478993}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:16478993}. Nucleus {ECO:0000269|PubMed:16478993}. Note=Predominant in the perinuclear region. Little protein in the nucleus.
Tissue Specificity Detected in peripheral blood leukocytes, bone marrow, adrenal gland, trachea, spinal cord, thyroid, lymph node and stomach. {ECO:0000269|PubMed:12119110}.

UNC45A (C-12) - sc-165861 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UNC45A (C-12): sc-165861. Western blot analysis of UNC45A expression in non-transfected: sc-117752 (A) and mouse UNC45A transfected: sc-127750 (B) 293T whole cell lysates.

UNC45A (H-105) - sc-292072 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
UNC45A (H-105): sc-292072. Western blot analysis of UNC45A expression in non-transfected: sc-117752 (A) and human UNC45A transfected: sc-175029 (B) 293T whole cell lysates.

UNC45A (T-12) - sc-165863 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

UNC45A (L-15) - sc-165862 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

UNC45A (AbS1) - sc-101493 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UNC45A (AbS1): sc-101493. Western blot analysis of UNC45A expression in non-transfected 293T: sc-117752 (A), human UNC45A transfected 293T: sc-115724 (B) and SK-N-SH (C) whole cell lysates.

UNC45A (D-6) - sc-390211 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UNC45A (D-6): sc-390211. Western blot analysis of UNC45A expression in non-transfected: sc-117752 (A) and human UNC45A transfected: sc-175029 (B) 293T whole cell lysates.

UNC45A (F-7) - sc-390231 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UNC45A (F-7): sc-390231. Western blot analysis of UNC45A expression in non-transfected: sc-117752 (A) and human UNC45A transfected: sc-175029 (B) 293T whole cell lysates.

UNC45A (H-1) - sc-390197 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
UNC45A (H-1): sc-390197. Western blot analysis of UNC45A expression in non-transfected: sc-117752 (A) and human UNC45A transfected: sc-175029 (B) 293T whole cell lysates.

Anti-UNC45A antibody - ab76905 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-UNC45A antibody (ab76905) at 5 µg/ml + human kidney tissue lysate at 25 µgSecondaryGoat anti Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-UNC45A antibody - ab108433 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-UNC45A antibody (ab108433) at 1 µg/ml + Human fetal lung lysate at 10 µg

Anti-UNC45A antibody - N-terminal - ab171328 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-UNC45A antibody - N-terminal (ab171328) at 1/100 dilution + A549 cell line lysate at 35 µg

Anti-UNC45A Antibody (aa146-174, AP) - LS-C273046 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC45A Antibody (aa146-174, APC) - LS-C273047 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC45A Antibody (aa146-174, Biotin) - LS-C273048 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC45A Antibody (aa146-174, FITC) - LS-C273049 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC45A Antibody (aa146-174, Azide-free, HRP) - LS-C273050 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC45A Antibody (aa146-174, PE) - LS-C273051 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC45A Antibody (aa153-182) - LS-C326196 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC45A Antibody (aa143-192) - LS-C117268 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UNC45A antibody LS-C117268 Western blot of Fetal Lung lysate.

Anti-UNC45A Antibody (C-Terminus) - LS-C111863 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
UNC45A antibody LS-C111863 Western blot of Fetal Thymus lysate.

Anti-UNC45A Antibody (aa146-174) - LS-C160433 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
UNC45A Antibody western blot of A549 cell line lysates (35 ug/lane). The UNC45A antibody detected the UNC45A protein (arrow).

Anti-UNC45A Antibody (clone AbS1) - LS-C343619 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone AbS1
Western blot of UNC45: Lane 1: MW marker, Lane 2: HeLa, Lane 3: 3T3, Lane 4: PC-12.

SMAP1 Antibody - NBP1-83702 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UNC45A Antibody - NBP2-13506 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UNC45A Antibody [NBP2-13506] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

UNC45A Antibody - NBP1-54882 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UNC45A Antibody [NBP1-54882] - Human Thymus lysate, concentration 0.2-1 ug/ml.
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