PIK3R5

Gene Symbol PIK3R5
Entrez Gene 23533
Alt Symbol F730038I15Rik, FOAP-2, P101-PI3K, p101
Species Human
Gene Type protein-coding
Description phosphoinositide-3-kinase, regulatory subunit 5
Other Description PI3-kinase p101 subunit|phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit|phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit|phosphoinositide 3-kinase regulatory subunit 5|protein FOAP-2|ptdIns-3-kinase p101
Swissprots Q8IZ23 Q5G938 D3DTS3 Q9Y2Y2 Q5G939 Q5G936 B0LPH4 Q8WYR1
Accessions ABY87553 AGC09603 EAW90035 EAW90036 EAW90037 Q8WYR1 AB028925 BAB82464 AF128881 AAD33397 AK129627 AK309074 AK314186 AY725851 AAW63121 AY725852 AAW63122 AY725853 AAW63123 AY725854 AAW63124 BC028212 AAH28212 XM_005256579 XP_005256636 XM_005256580 XP_005256637 XM_011523778 XP_011522080 NM_001142633 NP_001136105 NM_001251851 NP_001238780 NM_001251852 NP_001238781 NM_001251853 NP_001238782 NM_001251855 NP_001238784 NM_014308 NP_055123
Function Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity Ubiquitously expressed with high expression in fetal brain compared to adult brain. Abundant expression is observed in cerebellum, cerebral cortex, cerebral meninges, and vermis cerebelli. {ECO:0000269|PubMed:15797027, ECO:0000269|PubMed:22065524}.
Top Pathways Apoptosis, VEGF signaling pathway, Focal adhesion, Toll-like receptor signaling pathway, Jak-STAT signaling pathway

PIK3R5-Over-expression-Lysate - LY10075a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag PIK3R5 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PIK3R5 gene (Lane 2, Cat. #LY10075a).

PIK3R5 293 Cell Lysate - 402028 from ABBIOTEC

Category Cell Lysate
Prices $672.00
Sizes 100 µg

PIK3R5 Overexpression Lysate (Native) - NBL1-14424 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg

PIK3R5 Over-expression Lysate Product - GWB-DE9E61 from Genway Biotech

Category Cell Lysate
Prices $756.00
Sizes 100 µg
Species Human

PIK3R5 Overexpression Lysate (Native) - NBP2-09666 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: PIK3R5 Overexpression Lysate (Adult Normal) [NBP2-09666] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PIK3R5.

PIK3R5 Overexpression Lysate (Denatured) - H00023533-T02 from Novus Biologicals

Category Cell Lysate
Prices $299.00
Sizes 100 µl

Panoply™ Human PIK3R5 Knockdown Stable Cell Line - CSC-DC011792 from Creative biogene

Category Cell Line
Species Human
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