ACOT13

Gene Symbol ACOT13
Entrez Gene 55856
Alt Symbol HT012, PNAS-27, THEM2
Species Human
Gene Type protein-coding
Description acyl-CoA thioesterase 13
Other Description acyl-coenzyme A thioesterase 13|hypothalamus protein HT012|thioesterase superfamily member 2
Swissprots Q9NPJ3 O95549 F5H2L4
Accessions CAI93515 EAW55460 Q9NPJ3 AF155649 AAF67006 AF220186 AAF67651 AF274952 AAK07529 AK000508 BAA91215 AK309738 BC000894 AAH00894 BG568305 CB852340 DB214267 NM_001160094 NP_001153566 NM_018473 NP_060943
Function Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3- hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro). May play a role in controlling adaptive thermogenesis (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Mitochondrion {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=During interphase, found both in the nucleus and in the cytoplasm. At mitosis, localizes to the spindle. Colocalizes with tubulin (By similarity). {ECO:0000250}.

THEM2 (B-12) - sc-373696 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
THEM2 (B-12): sc-373696. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

THEM2 (F-3) - sc-514392 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
THEM2 (F-3): sc-514392. Western blot analysis of THEM2 expression in HeLa (A), Ramos (B), Hep G2 (C) and K-562 (D) whole cell lysates and human cerebellum (E) and human liver (F) tissue extracts.

THEM2 (C-12) - sc-169592 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
THEM2 (C-12): sc-169592. Western blot analysis of THEM2 expression in HeLa (A), Jurkat (B), Ramos (C) and MCF7 (D) whole cell lysates and mouse liver tissue extract (E).

THEM2 (E-15) - sc-169593 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
THEM2 (E-15): sc-169593. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes.

THEM2 (G-5) - sc-373697 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
THEM2 (G-5): sc-373697. Western blot analysis of THEM2 expression in Hep G2 whole cell lysate.

THEM2 (H-88) - sc-135431 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
THEM2 (H-88): sc-135431. Western blot analysis of THEM2 expression in Ramos whole cell lysate (A) and mouse liver tissue extract (B).

Anti-THEM2 antibody - ab70915 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-THEM2 antibody (ab70915) at 1/60 dilution + Mouse liver tissue lysates at 35 µg

Anti-THEM2 antibody - ab80386 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ab80386, at a 1/10 dilution, staining THEM2 in formalin fixed, paraffin embedded human hepatocarcinoma tissue by Immunohistochemistry. A peroxidase conjugated secondary antibody was used, followed by DAB staining.

Anti-THEM2 antibody - ab69072 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-THEM2 antibody (ab69072) at 1/500 dilutionLane 1 : THEM2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat anti-mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

Anti-THEM2 antibody - ab166684 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-THEM2 antibody (ab166684) at 0.05 µg/mlLane 1 : 293 cell lysateLane 2 : 293 cell lysate with immunizing peptideLane 3 : RAW cell lysate

Anti-ACOT13 / THEM2 Antibody (C-Terminus) IHC-plus™ - LS-B5012 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ACOT13 / THEM2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5012 concentration 5 ug/ml.

Anti-ACOT13 / THEM2 Antibody (clone 169CT7.1.3, Azide-free, HRP) - LS-C250448 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 169CT7.1.3

Anti-ACOT13 / THEM2 Antibody (clone 169CT7.1.3, PE) - LS-C250449 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 169CT7.1.3

Anti-ACOT13 / THEM2 Antibody (N-Terminus, AP) - LS-C283507 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACOT13 / THEM2 Antibody (N-Terminus, APC) - LS-C283509 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACOT13 / THEM2 Antibody (N-Terminus, Biotin) - LS-C283510 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACOT13 / THEM2 Antibody (N-Terminus, FITC) - LS-C283511 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACOT13 / THEM2 Antibody (aa100-150) IHC-plus™ - LS-B7954 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-THEM2 / ACOT13 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7954 dilution 10 ug/ml.

Anti-ACOT13 / THEM2 Antibody (N-Terminus, PE) - LS-C283512 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACOT13 / THEM2 Antibody (N-Terminus, Azide-free, HRP) - LS-C283513 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACOT13 / THEM2 Antibody (N-Terminus) - LS-C328880 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACOT13 / THEM2 Antibody - LS-C306058 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ACOT13 / THEM2 Antibody (clone 169CT7.1.3) - LS-C319213 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 169CT7.1.3

Anti-ACOT13 / THEM2 Antibody (aa25-75) - LS-C148425 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of THEM2 in human kidney lysate in the 1) absence and 2) presence of immunizing peptide 3) mouse kidney and 4) rat kidney using LS-C148425 at 0.5 ug/ml, 0.25 ug/ml and 0.25 ug/ml, respectively.

Anti-ACOT13 / THEM2 Antibody - LS-C161852 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
THEM2 Antibody western blot of HeLa cell line lysates (35 ug/lane). The THEM2 antibody detected the THEM2 protein (arrow).
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