Gene Symbol | ACOT13 |
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Entrez Gene | 55856 |
Alt Symbol | HT012, PNAS-27, THEM2 |
Species | Human |
Gene Type | protein-coding |
Description | acyl-CoA thioesterase 13 |
Other Description | acyl-coenzyme A thioesterase 13|hypothalamus protein HT012|thioesterase superfamily member 2 |
Swissprots | Q9NPJ3 O95549 F5H2L4 |
Accessions | CAI93515 EAW55460 Q9NPJ3 AF155649 AAF67006 AF220186 AAF67651 AF274952 AAK07529 AK000508 BAA91215 AK309738 BC000894 AAH00894 BG568305 CB852340 DB214267 NM_001160094 NP_001153566 NM_018473 NP_060943 |
Function | Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3- hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro). May play a role in controlling adaptive thermogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000250}. Mitochondrion {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Note=During interphase, found both in the nucleus and in the cytoplasm. At mitosis, localizes to the spindle. Colocalizes with tubulin (By similarity). {ECO:0000250}. |
Human THEM2 full length protein - ab101158 from Abcam
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Human THEM2 full length protein - ab88001 from Abcam
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ACOT13 / THEM2 Antibody Blocking Peptide - LS-E30737 from LifeSpan Bioscience
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THEM2 Recombinant Protein - H00055856-P01 from Novus Biologicals
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THEM2 Blocking Peptide - NBP1-77049PEP from Novus Biologicals
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Recombinant Human THEM2 Protein - NBP1-49166 from Novus Biologicals
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THEM2 Peptide - GTX85271-PEP from GeneTex
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ACOT13 Protein (OPPA02499) - OPPA02499 from Aviva Systems Biology
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THEM2 (His Tag) protein - orb171582 from Biorbyt
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Human ACOT13 protein - orb167841 from Biorbyt
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ACOT13 protein (His tag) - 80R-1493 from Fitzgerald
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THEM2 / ACOT13 (1-140, His-tag) - AR09669PU-L from Acris Antibodies
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THEM2 / ACOT13 (1-140, His-tag) - AR09669PU-N from Acris Antibodies
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THEM2 / ACOT13 - H00055856-P01-10 from Acris Antibodies
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THEM2 / ACOT13 - H00055856-P01-25 from Acris Antibodies
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THEM2 / ACOT13 Control Peptide - AP30875CP-N from Acris Antibodies
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Acyl-CoA Thioesterase 13, Human Recombinant - 228-12160-1 from RayBiotech
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Recombinant Human Acyl-CoA Thioesterase 13 - 228-12160-2 from RayBiotech
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Recombinant Human Acyl-CoA Thioesterase 13 - 228-12160-3 from RayBiotech
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ACOT13, 1-140aa, Human, His tag, E.coli - 01-2358-13 from ARP American Research Products
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THEM2 Peptide - 5257P from ProSci
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THEM2 fusion protein - Ag10212 from Proteintech Group
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THEM2 fusion protein - Ag10244 from Proteintech Group
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ACOT13 Human - ENPS-011 from NeoScientific
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Recombinant Human ACOT13 - BP000594-ENZ-004 from Syd Labs
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