Gene Symbol | Hhex |
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Entrez Gene | 15242 |
Alt Symbol | Hex, Hex1, Hhex-rs2, Prh, Prhx |
Species | Mouse |
Gene Type | protein-coding |
Description | hematopoietically expressed homeobox |
Other Description | hematopoietically expressed homeobox, related sequence 2|hematopoietically-expressed homeobox protein Hhex|homeobox protein HEX|homeobox protein PRH|mHex |
Swissprots | P43120 Q9R1X2 Q9CRV1 Q544N6 |
Accessions | AAF04349 BAA76714 CAA79729 EDL41790 P43120 AK014111 BAB29163 AK033664 BAC28416 AK149553 BC057986 AAH57986 NM_008245 NP_032271 |
Function | Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. {ECO:0000250, ECO:0000269|PubMed:10804173, ECO:0000269|PubMed:16936074}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Top Pathways | Maturity onset diabetes of the young, Transcriptional misregulation in cancer |
Anti-HHEX / HEX Antibody - LS-C67408 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (C-Terminus) - LS-C82011 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (Internal, clone EPR3361) - LS-C105532 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (clone 2H7) - LS-C114377 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa24-39, Magnetic beads) - LS-C172133 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa24-39, Sepharose) - LS-C172134 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (clone HHE5I261) - LS-C184257 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa24-39) - LS-C189380 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa201-250) - LS-C116002 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (C-Terminus) - LS-C116003 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (C-Terminus) - LS-C209874 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa244-270, Azide-free, HRP) - LS-C258442 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa244-270, PE) - LS-C258443 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa244-270, AP) - LS-C259744 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa24-39) - LS-C172132 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa244-270, APC) - LS-C259745 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa244-270, Biotin) - LS-C259746 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa244-270, FITC) - LS-C259747 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody - LS-C310606 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (clone 3F11) - LS-C197408 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa244-270) - LS-C159827 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (aa243-270) - LS-C321944 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody IHC-plus⢠- LS-B3077 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (clone 2H7) - LS-C114323 from LifeSpan Bioscience
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Anti-HHEX / HEX Antibody (clone HHE5I261) - LS-C342316 from LifeSpan Bioscience
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