| Gene Symbol | Hhex |
|---|---|
| Entrez Gene | 15242 |
| Alt Symbol | Hex, Hex1, Hhex-rs2, Prh, Prhx |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | hematopoietically expressed homeobox |
| Other Description | hematopoietically expressed homeobox, related sequence 2|hematopoietically-expressed homeobox protein Hhex|homeobox protein HEX|homeobox protein PRH|mHex |
| Swissprots | P43120 Q9R1X2 Q9CRV1 Q544N6 |
| Accessions | AAF04349 BAA76714 CAA79729 EDL41790 P43120 AK014111 BAB29163 AK033664 BAC28416 AK149553 BC057986 AAH57986 NM_008245 NP_032271 |
| Function | Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. {ECO:0000250, ECO:0000269|PubMed:10804173, ECO:0000269|PubMed:16936074}. |
| Subcellular Location | Nucleus {ECO:0000305}. |
| Top Pathways | Maturity onset diabetes of the young, Transcriptional misregulation in cancer |
Exonuclease 1 (EXO1), Mouse, ELISA Kit - CSB-EL007876MO from ARP American Research Products
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Prolactin-releasing hormone (PRH), Mouse, ELISA Kit - CSB-E14074m from ARP American Research Products
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hematopoietically expressed homeobox, ELISA Kit - MBS9328218 from MyBioSource
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Mouse Hhex ELISA Kit - E055408 from Biobool
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Mouse PRH ELISA Kit - E064740 from Biobool
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Mouse Prolactin-releasing hormone (PRH) ELISA Kit - AE26030MO from ARP American Research Products
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Mouse PRH ELISA Kit - orb409009 from Biorbyt
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