PNPLA6

Gene Symbol	PNPLA6
Entrez Gene	10908
Alt Symbol	BNHS, LNMS, NTE, NTEMND, OMCS, SPG39, iPLA2delta, sws
Species	Human
Gene Type	protein-coding
Description	patatin-like phospholipase domain containing 6
Other Description	neuropathy target esterase|patatin-like phospholipase domain-containing protein 6
Swissprots	F5H5K9 Q9UG58 O60859 B7Z7T2 Q8IY17 B4DFB9 A6NGQ0 Q86W58 J3KQS3
Accessions	AIL88793 AIL88794 AIL88795 AIL88796 AIL88797 AIL88798 AIL88799 EAW69029 EAW69030 Q8IY17 AJ004832 CAA06164 AK293807 BAG57214 AK294021 BAG57380 AK302462 BAH13718 AL050362 CAB43674 BC038229 AAH38229 BC050553 AAH50553 BC051768 AAH51768 BQ001677 BQ430066 DA096881 DA104284 DA247219 DB068563 NM_001166111 NP_001159583 NM_001166112 NP_001159584 NM_001166113 NP_001159585 NM_001166114 NP_001159586 NM_006702 NP_006693
Function	Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy. {ECO:0000269|PubMed:15044461, ECO:0000269|PubMed:1666291}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:15044461}; Single-pass type I membrane protein {ECO:0000269|PubMed:15044461}; Cytoplasmic side {ECO:0000269|PubMed:15044461}. Note=Anchored to the cytoplasmic face of the endoplasmic reticulum by its amino-terminal transmembrane segment.
Tissue Specificity	Expressed in brain, placenta, kidney, neuron and skeletal muscle. {ECO:0000269|PubMed:9576844}.
Top Pathways	Glycerophospholipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PNPLA6 Antibody Blocking Peptide - LS-E4048 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PNPLA6 Antibody Blocking Peptide - LS-E17009 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PNPLA6 Antibody Blocking Peptide - LS-E26968 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PNPLA6 Protein - H00010908-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PNPLA6-Antibody-C-term-Blocking-Peptide - BP16273b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NTE blocking peptide - GTX88262-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse

Pnpla6 Blocking Peptide - 33R-1944 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

NTE Peptide - AC21-1797-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NTE - H00010908-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NTE - H00010908-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NTE Peptide - 42-227P from ProSci Category Peptide Prices $175.00 Sizes 100 µg

PNPLA6 fusion protein - Ag5546 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human PNPLA6, His-tagged - PNPLA6-29926TH from Creative Biomart Category Protein Source E. coli

Recombinant Human PNPLA6, His-tagged - PNPLA6-1819H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Neuropathy Target Esterase (NTE) - RPH515Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Human Neuropathy target esterase(PNPLA6) ,partial - CSB-YP809011HU CSB-EP809011HU CSB-BP809011HU CSB-MP809011HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PNPLA6 Blocking Peptide - CBP4160 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse

PNPLA6 Blocking Peptide - abx161371 from Abbexa Category Peptide Species Human, Mouse

NTE (transcript variant 1) - TP328678 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NTE, Peptide - MBS425751 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

PNPLA6 Recombinant Protein Antigen - NBP1-80984PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PNPLA6 Peptide, Human - M34GP12041H from Creative Peptides Category Peptide Source Synthetic. Species Human

PNPLA6 Antibody - SH-A14627 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

PNPLA6 Immunizing peptide - orb15089 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

Neuropathy Target Esterase, Recombinant Protein - MBS2033249 from MyBioSource Category Protein Prices $190.00, $410.00, $635.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Rat

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