Gene Symbol | LURAP1 |
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Entrez Gene | 541468 |
Alt Symbol | C1orf190, LRAP35a, LRP35A |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich adaptor protein 1 |
Other Description | NF-kappa-B activator C1orf190|leucine repeat adapter protein 35A|leucine repeat adaptor protein 35a |
Swissprots | Q96LR2 |
Accessions | EAX06931 Q96LR2 AI077554 AK057892 BAB71608 BC034422 AAH34422 BX370151 CR746264 JF432640 ADZ15857 NM_001013615 NP_001013633 |
Function | Acts as an activator of the canonical NF-kappa-B pathway and drive the production of proinflammatory cytokines. Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway. In concert with MYO18A and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Activates CDC42BPA/CDC42BPB and targets it to actomyosin through its interaction with MYO18A, leading to MYL9/MLC2 phosphorylation and MYH9/MYH10-dependent actomyosin assembly in the lamella (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:21048106}. |
LURAP1 (G-13) - sc-163871 from Santa Cruz Biotechnology
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LURAP1 (H-100) - sc-382301 from Santa Cruz Biotechnology
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LURAP1 (S-14) - sc-163873 from Santa Cruz Biotechnology
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Anti-C1ORF190 antibody - ab91069 from Abcam
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Anti-C1orf190 Antibody (aa143-192) - LS-C111837 from LifeSpan Bioscience
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LURAP1 Antibody - NBP1-83569 from Novus Biologicals
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LURAP1 Antibody - NBP1-83568 from Novus Biologicals
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LURAP1 Antibody - NBP1-56823 from Novus Biologicals
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C1ORF190 Polyclonal Antibody - bs-15049R from Bioss
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C1ORF190 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15049R-A350 from Bioss
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C1ORF190 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-15049R-A488 from Bioss
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C1ORF190 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15049R-A555 from Bioss
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C1ORF190 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15049R-A647 from Bioss
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C1ORF190 Polyclonal Antibody, Cy3 Conjugated - bs-15049R-Cy3 from Bioss
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C1ORF190 Polyclonal Antibody, Cy5 Conjugated - bs-15049R-Cy5 from Bioss
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C1ORF190 Polyclonal Antibody, Cy5.5 Conjugated - bs-15049R-Cy5.5 from Bioss
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C1ORF190 Polyclonal Antibody, Cy7 Conjugated - bs-15049R-Cy7 from Bioss
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C1ORF190 Polyclonal Antibody, FITC Conjugated - bs-15049R-FITC from Bioss
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C1ORF190 Polyclonal Antibody, Biotin Conjugated - bs-15049R-Biotin from Bioss
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C1ORF190 Polyclonal Antibody, HRP Conjugated - bs-15049R-HRP from Bioss
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Anti-C1ORF190 antibody produced in rabbit - SAB2104162 from Sigma-Aldrich
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Anti-LURAP1 antibody produced in rabbit - HPA030060 from Sigma-Aldrich
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Anti-LURAP1 antibody produced in rabbit - HPA030061 from Sigma-Aldrich
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Anti-C1orf190 (196-209) antibody produced in rabbit - SAB1103932 from Sigma-Aldrich
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Anti-C1orf190 (8-20) antibody produced in rabbit - SAB1103931 from Sigma-Aldrich
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