Gene Symbol | LURAP1 |
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Entrez Gene | 541468 |
Alt Symbol | C1orf190, LRAP35a, LRP35A |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich adaptor protein 1 |
Other Description | NF-kappa-B activator C1orf190|leucine repeat adapter protein 35A|leucine repeat adaptor protein 35a |
Swissprots | Q96LR2 |
Accessions | EAX06931 Q96LR2 AI077554 AK057892 BAB71608 BC034422 AAH34422 BX370151 CR746264 JF432640 ADZ15857 NM_001013615 NP_001013633 |
Function | Acts as an activator of the canonical NF-kappa-B pathway and drive the production of proinflammatory cytokines. Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway. In concert with MYO18A and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Activates CDC42BPA/CDC42BPB and targets it to actomyosin through its interaction with MYO18A, leading to MYL9/MLC2 phosphorylation and MYH9/MYH10-dependent actomyosin assembly in the lamella (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:21048106}. |
C1orf190 Antibody Blocking Peptide - LS-E20363 from LifeSpan Bioscience
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C1ORF190 Blocking Peptide - 33R-8527 from Fitzgerald
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Recombinant Human Leucine rich adaptor protein 1(LURAP1) - CSB-YP842709HU CSB-EP842709HU CSB-BP842709HU CSB-MP842709HU from Cusabio
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LURAP1 Recombinant Protein Antigen - NBP1-83569PEP from Novus Biologicals
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LURAP1 Recombinant Protein Antigen - NBP1-83568PEP from Novus Biologicals
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LURAP1 Peptide, Human - M34GP08994H from Creative Peptides
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Leucine rich adaptor protein 1 (LURAP1), Recombinant Protein - MBS1402265 from MyBioSource
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