LURAP1

Gene Symbol	LURAP1
Entrez Gene	541468
Alt Symbol	C1orf190, LRAP35a, LRP35A
Species	Human
Gene Type	protein-coding
Description	leucine rich adaptor protein 1
Other Description	NF-kappa-B activator C1orf190|leucine repeat adapter protein 35A|leucine repeat adaptor protein 35a
Swissprots	Q96LR2
Accessions	EAX06931 Q96LR2 AI077554 AK057892 BAB71608 BC034422 AAH34422 BX370151 CR746264 JF432640 ADZ15857 NM_001013615 NP_001013633
Function	Acts as an activator of the canonical NF-kappa-B pathway and drive the production of proinflammatory cytokines. Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway. In concert with MYO18A and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Activates CDC42BPA/CDC42BPB and targets it to actomyosin through its interaction with MYO18A, leading to MYL9/MLC2 phosphorylation and MYH9/MYH10-dependent actomyosin assembly in the lamella (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:21048106}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

C1orf190-Over-expression-Lysate - LY14616a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

LURAP1 overexpression lysate - LY422980 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

C1orf190 293 Cell Lysate - 409837 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

LURAP1 Overexpression Lysate (Native) - NBL1-08309 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

C1orf190 Over-expression Lysate Product - GWB-CB7E46 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human LURAP1 Knockdown Stable Cell Line - CSC-DC008994 from Creative biogene Category Cell Line Species Human

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