PTH1R

Gene Symbol PTH1R
Entrez Gene 5745
Alt Symbol PFE, PTHR, PTHR1
Species Human
Gene Type protein-coding
Description parathyroid hormone 1 receptor
Other Description PTH/PTHr receptor|PTH/PTHrP type I receptor|PTH1 receptor|parathyroid hormone receptor 1|parathyroid hormone/parathyroid hormone-related peptide receptor|parathyroid hormone/parathyroid hormone-related protein receptor|seven transmembrane helix receptor
Swissprots Q03431 Q2M1U3
Accessions AAB60657 AAC27643 BAC05721 EAW64793 EAW64794 Q03431 AY449732 AAR18076 BC031578 BC110388 AAI10389 BC112221 AAI12222 BC112247 AAI12248 BQ574694 CA412652 HQ258471 ADR83225 L04308 AAA36525 U17418 AAA56774 X68596 CAA48589 XM_005265344 XP_005265401 XM_011533967 XP_011532269 XM_011533968 XP_011532270 NM_000316 NP_000307 NM_001184744 NP_001171673
Function This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. {ECO:0000269|PubMed:18611381, ECO:0000269|PubMed:20172855}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:20172855}; Multi-pass membrane protein {ECO:0000269|PubMed:20172855}.
Tissue Specificity Expressed in most tissues. Most abundant in kidney, bone and liver.
Top Pathways Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction

PTH/PTHrP-R CRISPR/Cas9 KO Plasmid (h) - sc-417487 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTH/PTHrP-R HDR Plasmid (h) - sc-417487-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTH/PTHrP-R Double Nickase Plasmid (h) - sc-417487-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTH/PTHrP-R Double Nickase Plasmid (h2) - sc-417487-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTH/PTHrP-R CRISPR Activation Plasmid (h) - sc-417487-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTH/PTHrP-R CRISPR Activation Plasmid (h2) - sc-417487-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTH/PTHrP-R Lentiviral Activation Particles (h) - sc-417487-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTH/PTHrP-R Lentiviral Activation Particles (h2) - sc-417487-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PTH/PTHrP-R siRNA (h) - sc-36327 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PTH/PTHrP-R shRNA Plasmid (h) - sc-36327-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PTH/PTHrP-R shRNA (h) Lentiviral Particles - sc-36327-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN17678 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17678 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00142 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00142

PTH1R siRNA (Human) - CRH3887 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PTH1R/PTHR1 RNAi - H00005745-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human PTH1R (NM_000316.2) - SHH386172 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PTHR1(NM_000316.2) - SHR150347 from Creative biogene

Category siRNA
Species Reactivities Human

Human PTH1R siRNA - orb264389 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PTH1R shRNA Plasmid (Human) - CHH3887 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PTH1R miRNA 3'UTR clone - MiUTR1H-08431 from Creative biogene

Species Reactivities Human
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