PTH1R

Gene Symbol	PTH1R
Entrez Gene	5745
Alt Symbol	PFE, PTHR, PTHR1
Species	Human
Gene Type	protein-coding
Description	parathyroid hormone 1 receptor
Other Description	PTH/PTHr receptor|PTH/PTHrP type I receptor|PTH1 receptor|parathyroid hormone receptor 1|parathyroid hormone/parathyroid hormone-related peptide receptor|parathyroid hormone/parathyroid hormone-related protein receptor|seven transmembrane helix receptor
Swissprots	Q03431 Q2M1U3
Accessions	AAB60657 AAC27643 BAC05721 EAW64793 EAW64794 Q03431 AY449732 AAR18076 BC031578 BC110388 AAI10389 BC112221 AAI12222 BC112247 AAI12248 BQ574694 CA412652 HQ258471 ADR83225 L04308 AAA36525 U17418 AAA56774 X68596 CAA48589 XM_005265344 XP_005265401 XM_011533967 XP_011532269 XM_011533968 XP_011532270 NM_000316 NP_000307 NM_001184744 NP_001171673
Function	This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. {ECO:0000269|PubMed:18611381, ECO:0000269|PubMed:20172855}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:20172855}; Multi-pass membrane protein {ECO:0000269|PubMed:20172855}.
Tissue Specificity	Expressed in most tissues. Most abundant in kidney, bone and liver.
Top Pathways	Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Parathyroid Hormone Receptor 1 protein fragment - ab182670 from Abcam Category Protein Prices $357.00 Sizes 100 µg Source HEK 293 cells Species Human

Human Parathyroid Hormone Receptor 1 protein fragment - ab152639 from Abcam Category Protein Source Wheat germ Species Human

PTHR / PTHR1 Antibody Blocking Peptide - LS-E29275 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PTHR / PTHR1 Antibody Blocking Peptide - LS-E29276 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human PTH1R/PTHR1 Protein - H00005745-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PTH1R/PTHR1 Protein - H00005745-G01-10ug from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Species Human

PTHrP recombinant protein - GTX65226 from GeneTex Category Protein Prices $199.00 Sizes 10 μg Source E. coli Species Human

PTHrP recombinant protein - GTX65225 from GeneTex Category Protein Prices $249.00 Sizes 50 μg Source E. coli Species Human

Recombinant Human PTH1R/PTHR1, CF - 5709-PR-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Tyr23-Met189, with a C-terminal 6-His tag

PTH Protein (OPPA01543) - OPPA01543 from Aviva Systems Biology Category Protein Prices $360.00 Sizes 100 µg Source E. Coli

Human PTH1R His tag protein - orb84565 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

PTHrP protein - 30R-2372 from Fitzgerald Category Protein Prices $100.00, $245.00 Sizes 10 µg, 50 µg Source E.coli Species Human

PTH Receptor 1 - H00005745-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PTH Receptor 1 - H00005745-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Parathyroid Hormone (7-34), Human Recombinant - 228-11343-1 from RayBiotech Category Protein Prices $294.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human PTH (aa 7-34) - 228-11343-2 from RayBiotech Category Protein Prices $588.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human PTH (aa 7-34) - 228-11343-3 from RayBiotech Category Protein Prices $948.00 Sizes 3 µg Source Escherichia Coli. Species Human

PEX, human - 12-4414 from ARP American Research Products Category Protein Prices $179.00 Sizes 5 µg Source Recombinant, Escherichia Coli expression system Species Human

PTHR1 Recombinant Protein - 96-641 from ProSci Category Protein Prices $375.00 Sizes 100 µg Source HEK293 cells Species Human

PTH1R fusion protein - ag17577 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

PTH1R fusion protein - ag4283 from Proteintech Group Category Protein Source E. coli-derived, T-HIS Species Human

PTH (7-34) Human - HOPS-273 from NeoScientific Category Protein Prices $260.00, $650.00, $1,040.00 Sizes 100 µg, 500 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human PTH1R, His tagged - PTH1R-7006H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human PTH1R - PTH1R-321H from Creative Biomart Category Protein Source Mammalian Cells Species Human

PTH (7-34) - RAB-322 from Reagent Proteins Category Protein Prices $350.00, $726.00, $997.00 Sizes 25 mg, 500.00 µg, 1 mg Source E.coli Species Human

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