Gene Symbol | APLP1 |
---|---|
Entrez Gene | 333 |
Alt Symbol | APLP |
Species | Human |
Gene Type | protein-coding |
Description | amyloid beta (A4) precursor-like protein 1 |
Other Description | APLP-1|amyloid precursor-like protein 1|amyloid-like protein 1 |
Swissprots | Q96A92 P51693 O00113 |
Accessions | AAB50173 P51693 AK092376 AK126907 AK297339 BAH12554 AK297640 BAH12638 AK312292 BAG35219 BC012889 AAH12889 BC013850 BC032983 BQ219233 DQ891341 ABM82267 DQ894523 ABM85449 EF036503 ABO65089 U48437 AAB96331 NM_001024807 NP_001019978 NM_005166 NP_005157 |
Function | May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. {ECO:0000250}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD). {ECO:0000269|PubMed:7494461}. |
APLP1 peptide - ab106419 from Abcam
|
||||||||||
Recombinant Human APLP-1 Protein - H00000333-Q01 from Novus Biologicals
|
||||||||||
APLP1 Protein Lysate (APL10376) - APL10376 from Aviva Systems Biology
|
||||||||||
APLP1 Protein Lysate (APL10377) - APL10377 from Aviva Systems Biology
|
||||||||||
Human APLP1 protein (His Tag) - orb138192 from Biorbyt
|
||||||||||
APLP1 peptide - orb216923 from Biorbyt
|
||||||||||
APLP1 Blocking Peptide - abx062254 from Abbexa
|
||||||||||
Amyloid-like protein 1 / APLP1 - H00000333-Q01-10 from Acris Antibodies
|
||||||||||
Amyloid-like protein 1 / APLP1 - H00000333-Q01-25 from Acris Antibodies
|
||||||||||
APLP1 fusion protein - Ag2951 from Proteintech Group
|
||||||||||
Amyloid Precursor Pro. N-term Peptide - GWB-93C24E from Genway Biotech
|
||||||||||
Recombinant Human APLP1, His-tagged - APLP1-26119TH from Creative Biomart
|
||||||||||
Recombinant Human APLP1, GST-tagged - APLP1-9745H from Creative Biomart
|
||||||||||
Recombinant Human APLP1, His tagged - APLP1-350H from Creative Biomart
|
||||||||||
Recombinant Amyloid Beta Precursor Like Protein 1 (APLP1) - RPG121Hu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Amyloid Beta Precursor Like Protein 1 (APLP1) - RPG121Mu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Amyloid Beta Precursor Like Protein 1 (APLP1) - RPG121Mu02 from Uscn Life Science Inc.
|
||||||||||
Human APLP1 / Amyloid-like protein 1 Protein (His Tag) - 13716-H08H-20 from Sino Biological
|
||||||||||
APLP1 Blocking Peptide - CBP1060 from Cohesion Biosciences
|
||||||||||
Recombinant Human Amyloid-like protein 1(APLP1) - CSB-YP001911HU CSB-EP001911HU CSB-BP001911HU CSB-MP001911HU from Cusabio
|
||||||||||
APLP1 Protein - abx164565 from Abbexa
|
||||||||||
Amyloid-like protein 1(APLP1) , Recombinant Protein - MBS961187 from MyBioSource
|
||||||||||
Recombinant Human APLP1 / Amyloid-like protein 1 Protein (His tag) - PKSH030570 from Elabscience
|
||||||||||
APLP-1 Protein - NBP1-89036PEP from Novus Biologicals
|
||||||||||
APLP-1 Recombinant Protein Antigen - NBP2-38140PEP from Novus Biologicals
|