Gene Symbol | APLP1 |
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Entrez Gene | 333 |
Alt Symbol | APLP |
Species | Human |
Gene Type | protein-coding |
Description | amyloid beta (A4) precursor-like protein 1 |
Other Description | APLP-1|amyloid precursor-like protein 1|amyloid-like protein 1 |
Swissprots | Q96A92 P51693 O00113 |
Accessions | AAB50173 P51693 AK092376 AK126907 AK297339 BAH12554 AK297640 BAH12638 AK312292 BAG35219 BC012889 AAH12889 BC013850 BC032983 BQ219233 DQ891341 ABM82267 DQ894523 ABM85449 EF036503 ABO65089 U48437 AAB96331 NM_001024807 NP_001019978 NM_005166 NP_005157 |
Function | May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. {ECO:0000250}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD). {ECO:0000269|PubMed:7494461}. |
APLP1 (H-70) - sc-367468 from Santa Cruz Biotechnology
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APLP1 (P-20) - sc-23818 from Santa Cruz Biotechnology
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Anti-APLP1 antibody - ab94957 from Abcam
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Anti-APLP1 antibody - ab192481 from Abcam
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Anti-APLP1 antibody [MM0661-7Q32] - ab201557 from Abcam
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Anti-APLP1 antibody - N-terminal - ab191066 from Abcam
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Anti-APLP1 / APLP-1 Antibody - LS-C341448 from LifeSpan Bioscience
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Anti-APLP1 / APLP-1 Antibody - LS-C335260 from LifeSpan Bioscience
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Anti-APLP1 / APLP-1 Antibody (aa101-120) - LS-C313214 from LifeSpan Bioscience
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APLP-1 Antibody (354020) - MAB3908 from Novus Biologicals
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APLP-1 Antibody [Unconjugated] - AF3129 from Novus Biologicals
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Myelin PLP Antibody (plpc1) - NBP1-50309 from Novus Biologicals
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APLP-1 Antibody (354008) - MAB3129 from Novus Biologicals
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APLP-1 Antibody - NBP2-38140 from Novus Biologicals
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APLP-1 Antibody - NBP1-89036 from Novus Biologicals
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APLP-1 Antibody - H00000333-B01P-50ug from Novus Biologicals
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APLP1 Polyclonal Antibody - bs-8465R from Bioss
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Anti-APLP1 antibody produced in mouse - SAB1412689 from Sigma-Aldrich
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Anti-APLP1 (556-570) antibody produced in rabbit - A4360 from Sigma-Aldrich
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Anti-APLP1 (511-525) antibody produced in rabbit - A4235 from Sigma-Aldrich
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APLP1 antibody - GTX12316 from GeneTex
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APLP1 antibody - GTX30055 from GeneTex
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Anti -APLP1 (Amyloid Precursor Like Protein 1, APLP) - 209541 from USBiological Life Science
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Anti -APLP1 (Amyloid-like Protein 1 Precursor, APLP 1, APLP, APLP-1, Aplp1, APLP1_HUMAN,C30,) - 220777 from USBiological Life Science
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Anti -APLP1 (amyloid precursor-like protein 1, amyloid-like protein 1) - 144178 from USBiological Life Science
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