APLP1

Gene Symbol	APLP1
Entrez Gene	333
Alt Symbol	APLP
Species	Human
Gene Type	protein-coding
Description	amyloid beta (A4) precursor-like protein 1
Other Description	APLP-1|amyloid precursor-like protein 1|amyloid-like protein 1
Swissprots	Q96A92 P51693 O00113
Accessions	AAB50173 P51693 AK092376 AK126907 AK297339 BAH12554 AK297640 BAH12638 AK312292 BAG35219 BC012889 AAH12889 BC013850 BC032983 BQ219233 DQ891341 ABM82267 DQ894523 ABM85449 EF036503 ABO65089 U48437 AAB96331 NM_001024807 NP_001019978 NM_005166 NP_005157
Function	May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. {ECO:0000250}.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD). {ECO:0000269|PubMed:7494461}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

APLP1 CRISPR/Cas9 KO Plasmid (h) - sc-403937 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

APLP1 HDR Plasmid (h) - sc-403937-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APLP1 Double Nickase Plasmid (h) - sc-403937-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APLP1 Double Nickase Plasmid (h2) - sc-403937-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APLP1 CRISPR Activation Plasmid (h) - sc-403937-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

APLP1 CRISPR Activation Plasmid (h2) - sc-403937-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

APLP1 Lentiviral Activation Particles (h) - sc-403937-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APLP1 Lentiviral Activation Particles (h2) - sc-403937-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

APLP1 siRNA (h) - sc-41907 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

APLP1 shRNA Plasmid (h) - sc-41907-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

APLP1 shRNA (h) Lentiviral Particles - sc-41907-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

APLP-1 RNAi - H00000333-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

APLP-1 RNAi - H00000333-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU033161 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3325 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3325 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02773 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr02773

APLP1 siRNA (Human) - CRH0234 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

APLP1 - MBS829608 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human APLP1 (NM_005166.3) - SHH238294 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human APLP1(NM_001024807.1) - SHG064873 from Creative biogene Category siRNA Species Reactivities Human

Human APLP1 siRNA - orb260736 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

APLP1 shRNA Plasmid (Human) - CHH0234 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

APLP1 miRNA 3'UTR clone - MiUTR1H-00466 from Creative biogene Species Reactivities Human

APLP1 miRNA 3'UTR clone - MiUTR1H-00467 from Creative biogene Species Reactivities Human

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